摘要： The ability of lasers to selectively destroy the melanin pigment responsible for solar/senile lentigines (SL) (age spots) without damaging the surrounding tissue makes laser therapy a preferred option for treating SL. However, laser therapies typically utilize a high energy output to achieve thermal ablation of their selective targets – and therefore can be associated with a period of recovery, healing and down time, depending on the modality. The Kleresca? biophotonic platform which generates fluorescent light energy (FLE), is a non-invasive form of photobiomodulation with multiple applications. FLE has clinical efficacy in treating inflammatory skin conditions such as acne vulgaris and rosacea, in addition to its healing and normalizing properties, rejuvenating the skin. It has previously been combined with other invasive treatment techniques; for example, following picosecond laser treatment of SL, where it enhanced the overall appearance of the skin. A common observation with the Kleresca? biophotonic platform is the transient emergence of underlying hyperpigmented spots. This case sought to investigate the use of the Kleresca? treatment to intensify and demask underlying SL prior to their targeting with laser therapy.