研究目的
Investigating the use of Near‐Infrared Spectroscopy (NIRS) to monitor tissue oxygenation, metabolism, and injury in low resource settings.
研究成果
NIRS is a non‐invasive, portable, easy to use and inexpensive technique to monitor tissue hemodynamics, oxygenation and metabolism in real time. It has been successfully used in low resource settings and can provide important information in diseases that are a burden in LMICs. The evidence shows that NIRS can be a useful monitor of health in low resource settings and holds significant potential in the diagnosis of disease as well as in monitoring treatment.
研究不足
The study is a review and does not present new experimental data. The applicability of NIRS in low resource settings may be limited by the availability of trained personnel and the need for further validation in diverse settings.
1:Experimental Design and Method Selection:
The study reviews the technology of NIRS, its use in healthcare and research, and current applications in low resource settings.
2:Sample Selection and Data Sources:
The study includes a literature search on the use of NIRS research on diseases prevalent in LMICs.
3:List of Experimental Equipment and Materials:
NIRS systems, including light sources with two or more wavelengths, optical fibers, and detectors.
4:Experimental Procedures and Operational Workflow:
The study describes the use of NIRS to monitor cerebral oxygenation and hemodynamics, and its application in various diseases.
5:Data Analysis Methods:
The study uses the modified Beer–Lambert law (MBLL) to estimate the relative concentration changes of HbO2 and HHb inside the tissue from the attenuation change.
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