研究目的
To retrospectively compare the efficacy of monopolar electrocautery (EC) with laser fibres in the treatment of patients affected by T1 or T2 oropharyngeal and supraglottic squamous cell carcinomas using transoral robotic surgery (TORS).
研究成果
Laser-TORS showed better results in comparison with EC-TORS in terms of tumour resection margins and functional outcomes, likely due to less severe thermal injury and more precise cutting properties of flexible laser fibres.
研究不足
The study is limited by its retrospective nature and the small number of patients, particularly in the subgroup of supraglottic cancers. Prospective randomized trials and a larger number of patients are needed to confirm these preliminary conclusions.
1:Experimental Design and Method Selection:
Retrospective analysis of TORS patients treated with Thulium:YAG laser (TY-TORS), CO2 laser (CO2-TORS), and monopolar electrocautery (EC-TORS) from January 2010 to June
2:Sample Selection and Data Sources:
20 Patients consecutively scheduled for TORS with laser or EC, performed by the same surgeon team, with cT1/T2 oropharyngeal and supraglottic squamous cell carcinomas, cN0/2, and cM0 at oncological staging.
3:List of Experimental Equipment and Materials:
Intuitive da Vinci S System, Endo Wrist Introducer, Thulium surgical laser fibres, Flexible CO2 Laser Fibre, monopolar EC, Maryland forceps, Feyh-Kastenbauer retractor.
4:Experimental Procedures and Operational Workflow:
Surgical robotic set-up as previously reported, with cutting tool handled in the left or right robotic arm relative to patient anatomy.
5:Data Analysis Methods:
Statistical analysis using Medcalc Version 19.0.5, with continuous variables compared using a Kruskal–Wallis test and categorical data compared using Fisher’s exact test.
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