研究目的
To compare the perioperative parameters of quadrant, sextant, and grid lens fragmentation patterns in femtosecond laser-assisted cataract surgery (FLACS) and to determine the optimal fragmentation pattern for different nuclear density grades.
研究成果
The grid pattern was better than the quadrant and sextant patterns in reducing EPT in soft nuclei (grade 1). All three patterns can be selected for treating grade 2 nuclei. In grade 3 nuclei, the sextant pattern exhibited the greatest reduction in energy consumption among the three patterns. The quadrant pattern allows for shorter phacoemulsification time and potentially lower US power in hard nuclei (grade 4 & 5). The grid pattern tended to result in greater temporary IOP elevation in hard nuclear cataracts, so this pattern should be chosen with caution in patients with glaucoma or glaucoma suspect.
研究不足
1. The patients were only followed up for one week postoperatively. 2. The sample size of patients with hard nuclear cataracts was rather limited. 3. Studying parameters regarding anterior chamber inflammation in the early postoperative period is also of great significance in evaluating the outcomes among the three fragmentation patterns.
1：Experimental Design and Method Selection:
A prospective randomized clinical trial was conducted to compare three fragmentation patterns (quadrant, sextant, and grid) in FLACS. The nuclear density was graded according to the Emery-Little classification.
2：Sample Selection and Data Sources:
A total of 894 eyes in 661 patients with cataracts were enrolled. Patients were randomized into three groups to undergo different fragmentation procedures.
3：List of Experimental Equipment and Materials:
A standard femtosecond laser platform (LenSx, Alcon, Inc.) and a phacoemulsification system (Stellaris, Bausch & Lomb, Inc.) were used.
4：Experimental Procedures and Operational Workflow:
All surgical procedures were performed by the same experienced surgeon. Patients received lens fragmentation using a quadrant, sextant, or grid pattern after random allocation. Evaluations included intraoperative parameters, complications, and postoperative outcomes.
5：Data Analysis Methods:
Data were analyzed using SPSS software. The Kolmogorov-Smirnov and/or Shapiro-Wilk tests were used to verify the normality of the quantitative variables. A one-way analysis of variance (ANOVA) was performed for group comparisons of normally distributed data.
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