摘要： Keratosis follicularis spinulosa decalvans (KFSD) is a rare genodermatosis characterized by widespread keratosis pilaris and progressive cicatricial alopecia of the scalp, eyebrows, and eyelashes; photophobia; and corneal dystrophy. We report a man with KFSD who was successfully treated with laser hair removal on the scalp. A 23-year-old man presented with an 8-year history of hair loss, which had started as a discrete 2.5-cm bald patch on the vertex of the scalp. He gradually developed more patches of alopecia, which expanded and coalesced, and in which the hair never regrew. He complained of itching and tenderness in the affected areas. Furthermore, he had dry skin, with rough-feeling bumps on the upper arms and thighs. As a child, he suffered with photophobia requiring the use of tinted spectacles, but this subsided during his teenage years. He had no other medical history of note and did not take any regular medication. He was of skin phototype II. There was a strong history of male pattern hair loss on the paternal side of the family.