研究目的
Investigating the therapeutic effects of neutron radiation therapy on cancer, particularly focusing on its advantages over low LET radiation for treating radiation-resistant and hypoxic tumors.
研究成果
Neutron radiation therapy, including BNCT, is a promising modality for treating certain types of cancer, offering advantages such as high LET, high RBE, and low OER. However, its clinical application is limited by challenges in boron delivery and the availability of neutron sources. Future advancements in accelerator technology and boron carriers may enhance its viability.
研究不足
The acceptance level of neutron radiation therapy in the medical community is not very high due to insufficient concentration of 10B at the tumor site and the limited number of operational nuclear research reactors. The development of boron-containing pharmaceuticals is at a low level.
