研究目的
To investigate the mathematical relationship between the BCG signal and the better-understood impedance cardiography (ICG) and arterial blood pressure (ABP) waveforms, and to determine if the BCG signal is more in accord with the pressure of the blood or its flow.
研究成果
The BCG is a signal more closely related to blood flow than pressures, and that a key health parameter for titrating care—stroke volume—can potentially be accurately measured with BCG signals at home using unobtrusive and inexpensive hardware, such as a modified weighing scale, as compared with the state-of-the-art ICG and ABP devices, which are expensive and obtrusive for use at home.
研究不足
An important limitation of this study was that data was collected from relatively young and healthy subjects. Future work should include a more diverse group of participants and also subjects with cardiovascular disease.
1:Experimental Design and Method Selection:
The study involved human subject studies designed to asynchronously modulate cardiac output and blood pressure with different magnitudes. System identification tools were used to explore the relationship between BCG, ICG, and ABP waveforms.
2:Sample Selection and Data Sources:
Nineteen healthy subjects were recruited for the study. Data were collected simultaneously with the BCG from each subject, including ICG, ECG, and ABP measurements.
3:List of Experimental Equipment and Materials:
ECG and ICG signals were measured using BN-EL50 and BN-NICO wireless measurement modules. The BCG was measured with a modified weighing scale. The arterial blood pressure was measured non-invasively with the A2SYS Nexfin Monitor.
4:Experimental Procedures and Operational Workflow:
The protocol consisted of five phases involving two perturbations separated by recovery time. All measurements were taken while the subject stood in an upright posture.
5:Data Analysis Methods:
The BCG, ICG, and ECG signals were filtered with finite impulse response (FIR) Kaiser window band-pass filters. Features were extracted from the ensemble-averaged traces of the BCG, ICG, and ABP signals.
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