研究目的
To overcome the limitation of recuperation in light-induced cross-coupling reactions using palladium functionalized gold nanoparticles by developing a palladium functionalized Fe3O4/Au core-shell nanoparticle that can be easily removed using magnetic precipitation and induces local heating via plasmon resonance.
研究成果
The Fe3O4/Au/PEG/Pd core-shell nanoparticle catalyst was successfully used for plasmonic heating in Suzuki cross-coupling reactions, with easy recovery via magnetic precipitation. However, its application was limited to reactions that could proceed at the temperatures achievable with plasmonic heating (40-45 °C), excluding Sonogashira reactions which require higher temperatures.
研究不足
The catalyst system was not effective for light-induced Sonogashira reactions due to insufficient heat generation at the catalytic site. The temperature at the catalytic site was limited to between 40 °C and 45 °C, which was not sufficient for Sonogashira reactions requiring higher temperatures.
1:Experimental Design and Method Selection:
The study involved the synthesis of a palladium functionalized Fe3O4/Au core-shell nanoparticle catalyst. The methodology included the use of plasmon resonance for local heating and magnetic precipitation for catalyst recovery.
2:Sample Selection and Data Sources:
The catalyst was tested in Suzuki and Sonogashira cross-coupling reactions under various conditions to evaluate its efficiency and recyclability.
3:List of Experimental Equipment and Materials:
Fe3O4/Au/PEG core-shell nanoparticles, palladium acetate, 1,4-dioxane, argon atmosphere, magnetic field for precipitation, UV-Vis spectrometer for plasmon resonance measurement.
4:Experimental Procedures and Operational Workflow:
The functionalization of nanoparticles with Pd was performed under argon atmosphere. The Suzuki and Sonogashira reactions were conducted under light irradiation at 680 nm. The catalyst was recovered using magnetic precipitation and reused in multiple cycles.
5:Data Analysis Methods:
The conversion rates were determined by 1H NMR using an internal standard. The amount of Pd on the catalyst was measured using ICP-AES.
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