研究目的
To investigate the effects of laser temporal pulse shaping of the super pulse Thulium fiber laser (SPTFL) and to compare them in controlled in vitro conditions with various Ho:YAG pulse delivery modes.
研究成果
Magnitude and initial velocity of stone retropulsion decrease with longer pulse duration and lower pulse peak power, but without sacrificing ablation efficiency. The novel SPTFL provides greater versatility and control of pulse parameters than Ho:YAG laser. Further clinical investigation of practical benefits achievable with pulse-shaping SPTFL modes is warranted.
研究不足
The study's pre-clinical nature limits clinical generalizability of the findings. Artificial stones were used, which may not fully replicate natural stone behavior. The lack of clinically standardized parameters for SPTFL prevented translation of laboratory findings to everyday practice.
1：Experimental Design and Method Selection:
The study compared the SPTFL and Ho:YAG lasers in terms of pulse shape, stone retropulsion, and ablation efficiency using artificial stone phantoms.
2：Sample Selection and Data Sources:
Artificial stone phantoms made from BegoStone powder were used.
3：List of Experimental Equipment and Materials:
SPTFL (Urolase SP, IRE-Polus), Ho:YAG laser (P120H, Lumenis), power meter (FieldMax II, Coherent), InGaAs photodiode (G12182-003K, Hamamatsu Photonics), digital oscilloscope (DSO-X 3034A, Agilent Technologies), high-speed camera (MIRO M310, Phantom Vision Research), scanning electron microscope (MIRA 3 LMU, Tescan), optical profilometer (8300, Zygo Corporation).
4：Experimental Procedures and Operational Workflow:
The distal fiber tip was brought into contact with the stone, and a high-speed camera captured stone movement. Pulse shapes were analyzed using a power meter and photodiode connected to an oscilloscope.
5：Data Analysis Methods:
Stone displacement and speed were analyzed using image processing software (ImageJ, NIH USA). Ablation volumes were computed using SEM and optical profilometer data.
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