研究目的
To compare the effectiveness and safety of mechanical microkeratome versus femtosecond laser in LASIK for adults with myopia.
研究成果
Regarding the visual acuity outcomes, there may be no difference between LASIK with mechanical microkeratome and LASIK with femtosecond laser. Dry eye and diffuse lamellar keratitis are likely adverse events with mechanical microkeratome and femtosecond laser, respectively. The evidence is uncertain regarding corneal haze and epithelial ingrowth as adverse events of each intervention.
研究不足
The limited number of outcomes reported in the included trials, some with potentially significant risk of bias, makes it difficult to draw a firm conclusion regarding the effectiveness and safety of the interventions investigated in this review.
1：Experimental Design and Method Selection:
Randomized controlled trials (RCTs) comparing mechanical microkeratome with femtosecond laser in LASIK for adults with myopia or myopic astigmatism.
2：Sample Selection and Data Sources:
Adults aged 18 years or older with more than
3：5 diopters of myopia or myopic astigmatism. List of Experimental Equipment and Materials:
Mechanical microkeratome and femtosecond laser for flap creation, excimer laser for corneal reshaping.
4：Experimental Procedures and Operational Workflow:
Creation of corneal flap with either mechanical microkeratome or femtosecond laser followed by corneal reshaping with excimer laser.
5：Data Analysis Methods:
Standard methodological procedures expected by Cochrane, including risk ratio (RR) for dichotomous outcomes and mean difference (MD) for continuous outcomes.
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