研究目的
Investigating the therapeutic effects of magnetic resonance thermography-guided laser interstitial therapy on brainstem cavernous malformations after recurrent hemorrhage.
研究成果
MR thermography-guided LITT may be a safe and effective treatment for brainstem CMs in select patients, as evidenced by symptomatic improvement and hemorrhage-free survival in the two cases presented. However, larger case numbers and longer follow-up are needed to substantiate these findings.
研究不足
The study involves a limited sample size and follow-up, and further studies are needed to assess reproducibility of findings, patient safety, technical nuances, and long-term reduction in hemorrhage risk.
1：Experimental Design and Method Selection:
The study retrospectively reviewed two cases of patients with pontine CMs treated with MR thermography-guided LITT.
2：Sample Selection and Data Sources:
Two consecutive patients with progressive neurological deficits due to recurrent hemorrhage of pontine CMs.
3：List of Experimental Equipment and Materials:
Visualase system (Medtronic, Minneapolis, MN, USA) and intraoperative MR imaging (IMRIS, Minnetonka, MN, USA).
4：Experimental Procedures and Operational Workflow:
Patients underwent LITT treatment using a frontal transcapsular approach and a suboccipital, transpeduncular approach.
5：Data Analysis Methods:
Clinical and radiographic information was collected by retrospective chart review.
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