研究目的
To review the evolution of mid-infrared (MIR) sensing technologies, with a special focus on photoacoustic spectroscopy, and its application in exhaled breath biomarker detection for non-invasive diagnostics.
研究成果
Mid-infrared point-of-care instrumentation promises high sensitivity and inherent molecular selectivity for breath analysis. However, overcoming the lack of standardization and understanding the pathobiology of breath compounds are essential for translating these techniques into widespread real-time clinical use.
研究不足
The variability of breath measurements and the lack of standardization of the various techniques are significant challenges. Additionally, the pathobiology of breath compounds needs extensive study to establish diagnostically relevant correlations between biomarkers and diseases.
