研究目的
To assess the feasibility of macular integrity assessment (MAIA) microperimetry (MP) in children. Also to establish representative outcome measures (differential light sensitivity, ?xation stability, test–retest reliability) for children without visual impairment.
研究成果
Microperimetry is feasible in 9- to 12-year-old children. However, systematically lower sensitivities mean that the classification boundary for "healthy" performance should be lowered in children, pending development of techniques to improve attentiveness/?xation that may reduce or remove this difference. High measurement variability suggests that the results of multiple tests should be averaged when possible. Learning effects are a potential confound, and it is recommended that the results of the ?rst examination be discarded.
研究不足
The physical con?guration of the current MAIA device limited testing to children aged 9 years and older. Younger children were too small to operate the MP comfortably. The study also noted that children exhibited poorer test–retest reliability and systematically lower sensitivities than adults, suggesting the need for adjusted classification boundaries for healthy performance in children.
1:Experimental Design and Method Selection:
Participants were 33 children (
2:2–9 years) and 33 adults (8–1 years), with no known visual problems or medical conditions and no previous experience of perimetry. Microperimetry assessments were carried out using the MAIA (Centervue, Padova, Italy). Sample Selection and Data Sources:
Normal vision was assessed by an Early Treatment Diabetic Retinopathy Study (ETDRS) recognition acuity chart and a brief parental questionnaire.
3:List of Experimental Equipment and Materials:
MAIA microperimeter (Centervue, Padova, Italy), ETDRS recognition acuity chart.
4:Experimental Procedures and Operational Workflow:
Participants completed three MP examinations within a single session. Examinations used the MAIA’s default test parameters and its standard 108/37-point test pattern. All testing was conducted monocularly, with the participant’s nondominant eye patched, and testing took place in a quiet, darkened room.
5:Data Analysis Methods:
Data were analyzed in Matlab (The Mathworks, Natick, MA, USA). For all statistics, 95% con?dence intervals (CI95) were computed via bootstrapping (n ? 20,000), using the bias-corrected and accelerated-percentile (BCa) method.
独家科研数据包,助您复现前沿成果,加速创新突破
获取完整内容