摘要： A pH and thermal stable three dimensional framework [Mg(ATDC)(H2O)2]n (1) (H2ATDC = 2'-amino-1,1':4',1''-terphenyl-4,4''-dicarboxylate) with blue fluorescence has been successfully synthesized and characterized. The Mg-MOF contains 2D [Mg(COO)2]n sheet, which links ATDC2- to generate 3D framework with accessible -NH2 groups, which could be beneficial to impact the reorganization on specific small molecules. Importantly, it is the first reported highly selective fluorescence Mg-MOF for sensing 2,4,6-Trinitrotoluene (TNT), and have the highest sensitivity for detecting Chromium(III) simultaneously through fluorescence quenching. Furthermore, the quenching mechanisms are mainly attributed to the photo-induced electron transfer and competitive absorptions between the excitation/emission of Mg-MOF and analytes, rather than the interactions between –NH2 and analytes.