研究目的
To review the popular emerging IMS technique and some unique optical imaging techniques for biological sample analysis.
研究成果
IMS is becoming a powerful tool for imaging complex biological samples, offering detailed molecular analysis without labeling. Despite its advantages, challenges remain in sample preparation, data processing, and 3D imaging. Chemiluminescence imaging shows promise for in vivo applications, with strategies to improve sensitivity and persistence. Dual-modal bioimaging combines the strengths of different imaging modalities for more accurate disease detection.
研究不足
The review highlights the limitations of IMS technology, including the need for high-throughput imaging, sample preparation techniques, and data processing methods. It also mentions the challenges in chemiluminescence imaging, such as low emission intensity and short emission wavelength.