研究目的
To develop an alternative method for improving the wettability and biocompatibility of polyamide 12 (PA12) angioplasty balloon catheters through photochemical reaction with a hydrophilic aromatic azide.
研究成果
The photochemical reaction of aromatic azides with PA12 can improve the wettability of PA12 angioplasty balloon catheters without deteriorating their mechanical performance. The method provides stable surface properties over time, which is advantageous for applications requiring long-term stability.
研究不足
The photochemical surface treatment induced a 15% reduction of the static contact angle, which is less than that reported for plasma treatments. The reaction yield was not high enough to allow the formation of a homogeneous surface coating, leading to increased chemical heterogeneity.
1：Experimental Design and Method Selection:
The study employed a photochemical reaction of PA12 with a hydrophilic aromatic azide (TRISAz) to modify the surface properties of PA12 angioplasty balloons. The reaction was initiated by UV irradiation at 254 nm.
2：Sample Selection and Data Sources:
PA12 angioplasty balloons and plates were used as samples. The balloons were manufactured from medical-grade PA12 pellets.
3：List of Experimental Equipment and Materials:
UV-C monochromatic lamps (model: G8T5 8 from Sankyo Denki), Thermo Fischer Evolution 220 spectrophotometer, DataPhysics OCA 15Pro contact angle instrument, Attension KSV 700 force tensiometer, PerkinElmer PHI 5400 ESCA System for XPS analysis, and a computer-controlled device (Crescent Design, model: HBLT 1000) for compliance tests.
4：Experimental Procedures and Operational Workflow:
The samples were dipped in a TRISAz solution, irradiated with UV light, cleaned with isopropyl alcohol, and then subjected to various tests including contact angle measurements, XPS analysis, and compliance tests.
5：Data Analysis Methods:
The surface free energy was evaluated using the van Oss, Good, and Chaudhury method. Contact angle data were analyzed to assess wettability, and XPS was used to confirm the presence of TRISAz on the PA12 surface.
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