研究目的
Investigating the qualities and thermal effects of a novel electrosurgical device for focused preparation in breast surgery compared to a standard device in a porcine ex vivo breast model.
研究成果
The novel electrosurgical prototype (PT) significantly reduces epicutaneous temperature and the slope of temperature rise compared to the standard device (SD), likely due to more focused energy application. The choice of device and mode (e.g., AutoCut + PT) can achieve up to 67% temperature reduction, potentially decreasing thermal complications in breast surgery. Future in vivo studies are needed to confirm these findings in human tissue.
研究不足
The study is based on an ex vivo porcine model with non-perfused tissue at room temperature, which may not fully replicate in vivo human conditions. Long-term thermal effects and absolute effects in vital human tissue are not addressed, requiring further in vivo investigation.
1：Experimental Design and Method Selection:
The study compared a novel electrosurgical prototype (PT) with a standard device (SD) in different modes (DryCut and AutoCut) using an ex vivo porcine breast model to assess thermal effects via infrared thermography. The rationale was to evaluate the reduction of thermal damage to adjacent tissue.
2：Sample Selection and Data Sources:
42 abdominal wall specimens from porcine tissue (skin, subcutaneous, and muscle layers) were used, sourced from Dr. Schenk experimental laboratory, Tübingen, stored at 8°C and brought to room temperature before experiments. Specimens were cut to 10x6x2 cm pieces.
3：List of Experimental Equipment and Materials:
Electrosurgical devices (PT prototype and SD, Ref. Nr. 21191-002, both from ERBE Elektromedizin GmbH), HF-Generator (Vio 300D, ERBE Elektromedizin GmbH), infrared camera (VarioCam, Jenoptik, Germany), porcine tissue specimens, cannula for marking.
4：Experimental Procedures and Operational Workflow:
Specimens were dissected alternately with PT or SD in DryCut or AutoCut modes. A cannula was placed 3 cm deep to mark a target line. The epicutaneous temperature was continuously measured using the infrared camera during preparation, focusing on maximum temperature and slope of temperature rise.
5：Data Analysis Methods:
Statistical analysis included Kolmogorov-Smirnov test for normal distribution, Student's t test, f test, Welch's t test, and Mann-Whitney test with significance level α=0.05. ΔTmax and slope of temperature rise were calculated and compared.
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