研究目的
To evaluate the influence of different levels of monovision on the clinical outcomes achieved with an extended range of vision (ERV) intraocular lens (IOL).
研究成果
Mini-monovision of around 0.75 D with the Tecnis Symfony IOL provides optimal visual rehabilitation, balancing good visual acuity across distances, minimal photic phenomena, and high patient satisfaction. Higher monovision levels may worsen intermediate vision, and future studies should assess stereopsis and long-term effects.
研究不足
The study is a subanalysis with potential biases from retrospective data collection. It does not evaluate long-term outcomes or stereopsis. The sample sizes for higher monovision groups (e.g., group 6 with 19 patients) are small, which may affect generalizability.
1：Experimental Design and Method Selection:
A subanalysis of the multicenter CONCERTO study was conducted, stratifying patients into six groups based on the postoperative magnitude of monovision (difference in spherical equivalent between eyes). Visual acuity, spectacle independence, photic phenomena, and patient satisfaction were evaluated.
2：Sample Selection and Data Sources:
411 patients from 40 study sites in Finland, France, Germany, Norway, Spain, Sweden, and the UK were included, with inclusion criteria such as visually significant cataract, bilateral implantation of the Tecnis Symfony IOL, age ≥18 years, and postoperative corneal astigmatism ≤0.75 D. Data were collected retrospectively and prospectively.
3：75 D. Data were collected retrospectively and prospectively.
List of Experimental Equipment and Materials:
3. List of Experimental Equipment and Materials: Tecnis Symfony IOL (Johnson & Johnson Vision), UNFOLDER Platinum 1 Series Screw-Style Inserter (Johnson & Johnson Vision), optical biometry, keratometry, slit lamp, Goldmann tonometry.
4：Experimental Procedures and Operational Workflow:
Patients underwent standard phacoemulsification surgery under topical anesthesia with mydriatic drops. Postoperative examinations at 4-8 weeks and 4-6 months included visual acuity measurements, refraction, and patient questionnaires on spectacle use, photic phenomena, and satisfaction.
5：Data Analysis Methods:
Means, standard deviations, and confidence intervals were calculated for visual acuities. Percentages for categorical data were determined. SPSS version 15.0 was used for statistical analysis.
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