研究目的
To investigate the feasibility and outcomes of performing small-incision lenticule extraction (SMILE) in a patient with high astigmatism and nystagmus, leveraging the procedure's ability to immobilize the cornea during treatment.
研究成果
SMILE is a feasible and effective treatment option for patients with nystagmus and high astigmatism, providing good visual outcomes and centered treatments due to corneal immobilization under suction. This case suggests that SMILE may offer advantages over other refractive surgeries in such patients, but larger controlled studies are needed to confirm these findings and compare with eye-tracking systems.
研究不足
The study is limited to a single case, which may not be generalizable. The lack of a control group or larger sample size restricts the ability to draw broad conclusions. Potential areas for optimization include developing better centration techniques for nystagmus patients and incorporating cyclotorsion control in SMILE procedures.
1：Experimental Design and Method Selection:
A case report design was used to evaluate SMILE in a patient with nystagmus and high astigmatism. The rationale was to assess the procedure's centration and effectiveness due to corneal immobilization under suction. Theoretical models included corneal topography and tomography for preoperative assessment.
2：Sample Selection and Data Sources:
The sample was a single 37-year-old male patient with congenital nystagmus and high astigmatism, selected based on suitability for refractive surgery. Data sources included clinical examinations, manifest refraction, corneal topography, tomography, contrast sensitivity tests, and postoperative follow-ups.
3：List of Experimental Equipment and Materials:
Equipment included ATLAS 9000 corneal topographer (Carl Zeiss Meditec AG), Orbscan IIz and Pentacam tomographers (Bausch & Lomb, Inc. and Oculus Optikger?te GmbH), CSV-1000 contrast sensitivity tester (VectorVision, Inc.), Corneo-Gauge Plus ultrasound pachymeter (Sonogage, Inc.), VisuMax femtosecond laser (Carl Zeiss Meditec AG), and RTVue optical coherence tomography (Optovue, Inc.). Materials included standard surgical instruments for SMILE.
4：Experimental Procedures and Operational Workflow:
Preoperative assessments included visual acuity, refraction, topography, tomography, contrast sensitivity, and pachymetry. SMILE was performed using the VisuMax laser with careful docking to ensure centration on the visual axis, using a printout guide. The cornea was immobilized by suction during lenticule creation. Postoperative evaluations at one year included visual acuity, refraction, topography, and OCT scans.
5：Data Analysis Methods:
Data were analyzed descriptively, comparing preoperative and postoperative visual outcomes, refraction, and corneal topography. Statistical techniques were not specified, as it is a case report.
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