研究目的
To describe a clinical case of successful conservative management of Localized Juvenile Spongiotic Gingivitis Hyperplasia (LJSGH) using photodynamic therapy (PDT) and reviews the current literature on this pathology.
研究成果
PDT proved to be a safe, quick, painless, and effective conservative treatment for LJSGH, with significant reduction in gingival hyperplasia and no esthetic harm over a 2-year follow-up. It offers advantages over invasive surgical methods, but more clinical studies are required to validate long-term efficacy.
研究不足
The report is limited to a single-patient case observation. The effects of PDT and laser therapy may be overlapped, and it is unclear if the improvement is due to PDT alone or combined with laser effects. Further prospective studies are needed to confirm observations and optimize treatment parameters.
1:Experimental Design and Method Selection:
A case report design was used, involving a single patient with LJSGH. The method selected was photodynamic therapy (PDT) with a low-level laser, adapted from protocols for oral lichen planus.
2:Sample Selection and Data Sources:
A 9-year-old male patient diagnosed with LJSGH based on clinical and histopathological examination. Data sources included clinical observations and literature review from databases like PubMed, Scopus, Web of Science, Scielo, and gray literature up to March
3:List of Experimental Equipment and Materials:
20 Methylene blue (
4:1%) as photosensitizer, DMC Therapy XT semiconductor laser diode (manufacturer:
MMO, S?o Carlos, S?o Paulo, Brazil).
5:Experimental Procedures and Operational Workflow:
Topical application of methylene blue for 5 minutes on the gingival sulcus and marginal gingiva, followed by laser irradiation. Laser parameters: wavelength 660 nm, power output 100 mW, continuous wave mode, spot area
6:028 cm2, exposure time 60 seconds per point, 9 application points per session. A total of 12 sessions were performed over 1 month (3 sessions per week on nonconsecutive days). Data Analysis Methods:
Clinical assessment of gingival hyperplasia reduction and erythema improvement through visual inspection and photography over a 2-year follow-up period.
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