- 标题
- 摘要
- 关键词
- 实验方案
- 产品
-
Photodynamic Therapy in Bowen Disease of the First Web Space of the Hand
摘要： Bowen disease (BD), or intraepithelial squamous cell carcinoma (SCC), may progress to an invasive SCC. Although surgery is preferred because of the low recurrence rate, it can result in hypertrophic scarring or contracture, particularly in lesions on the hands. We report a case of BD in the first web space of the hand, which was treated with ablative fractional laser-assisted photodynamic therapy (AFXL-assisted PDT). After multiple AFXL-assisted PDT sessions, the lesion showed no clinical or pathological abnormalities. Thus, we believe that PDT can be an alternative treatment for BD occurring in the web space of the hand.
关键词： Bowen's disease,Photodynamic therapy
更新于2025-09-23 15:23:52
-
Photomedicine - Advances in Clinical Practice || Photodynamic Therapy
摘要： Photodynamic therapy (PDT) employs light activation of tissue‐localized photosensitizer in an oxygen‐dependent process which initiates oxidative stress, inflammation, and cell death. Photodynamic therapy (PDT) involves the activation of a previously administered photosensitizing agent by visible light to induce tumor necrosis. Photosensitizers are topically applied in the treatment of skin tumors to avoid systemic side effects. The main dermatology indications for topical PDT are superficial nonmelanoma skin cancer and dysplasia, notably superficial basal carcinoma (BCC), Bowen's disease (BD), and actinic keratosis (AK). In this chapter, we evaluated the feasibility and efficacy of aminolevulinic acid (ALA) as a photosensitizer (ALA‐PDT) in combination with CO2 laser in the treat‐ment of dermatological disease from basics to clinic research.
关键词： photosensitizer,photodynamic therapy,Bowen's disease,actinic keratosis,aminolevulinic acid
更新于2025-09-09 09:28:46