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A near-infrared BODIPY-based fluorescent probe for ratiometric and discriminative detection of Hg2+ and Cu2+ ions in living cells
摘要： A near-infrared distyryl boron dipyrromethene-based sensor bearing one bis(1,2,3-triazole)amino receptor has been synthesized. This probe selectively and quickly binds to Hg2+ and Cu2+ ions in CH3CN/H2O (5:1 v/v) and exhibits remarkably blue-shifted absorption and fluorescence bands due to the inhibition of the intramolecular charge transfer process. The fluorescence changes of this probe upon binding to Hg2+ or Cu2+ ion are totally different, undergoing a ratiometric fluorescence enhancement (for Hg2+) or a fluorescence quenching (for Cu2+) mechanism. The corresponding vivid color changes can be easily seen by the naked eye. This probe was further introduced into Hela cells for living cell imaging and found to discriminate Hg2+ and Cu2+ ions through two near-infrared fluorescence emission channels. These overall results indicate that this Click-derived near-infrared BODIPY-based probe is potentially useful for ratiometric and discriminative detection of Hg2+ and Cu2+ ions in solutions and living cells.
关键词： Discriminative detection,Ratiometric,Hg2+ and Cu2+ sensor,Near-infrared,BODIPY
更新于2025-11-21 11:08:12
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White light emission from a mixture of silicon quantum dots and gold nanoclusters and its utilities in sensing of mercury( <scp>ii</scp> ) ions and thiol containing amino acid
摘要： White light emitting mixture (WLEM) was produced by controlled mixing of blue emitting silicon quantum dots (Si QDs) and orange red emitting gold nanoclusters (Au NCs). The chromaticity color co-ordinate of the WLEM studied using CIE (Commission Internationale del'Eclairage) diagram was found to be (0.33, 0.32), which was very close to that of perfect white light emitting source. The WLEM can also be achieved in the form of gel, solid and film with nearly the same CIE co-ordinates which enhances its utility as white light-emitting source in solid state devices. The reversible and thermo-responsive behaviour of the WLEM broadens its application in thermal sensing. Furthermore, the system was found to be showing fast, sensitive and selective detection of Hg2+ ions and thiol containing amino acid cysteine.
关键词： Hg2+ ions,white light emitting mixture,silicon quantum dots,cysteine,gold nanoclusters
更新于2025-11-20 15:33:11
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Highly Photoluminescent and Stable N-Doped Carbon Dots as Nanoprobes for Hg2+ Detection
摘要： We developed a microreactor with porous copper fibers for synthesizing nitrogen-doped carbon dots (N-CDs) with a high stability and photoluminescence (PL) quantum yield (QY). By optimizing synthesis conditions, including the reaction temperature, flow rate, ethylenediamine dosage, and porosity of copper fibers, the N-CDs with a high PL QY of 73% were achieved. The PL QY of N-CDs was two times higher with copper fibers than without. The interrelations between the copper fibers with different porosities and the N-CDs were investigated using X-ray photoelectron spectroscopy (XPS) and Fourier Transform infrared spectroscopy (FTIR). The results demonstrate that the elemental contents and surface functional groups of N-CDs are significantly influenced by the porosity of copper fibers. The N-CDs can be used to effectively and selectively detect Hg2+ ions with a good linear response in the 0~50 μM Hg2+ ions concentration range, and the lowest limit of detection (LOD) is 2.54 nM, suggesting that the N-CDs have great potential for applications in the fields of environmental and hazard detection. Further studies reveal that the different d orbital energy levels of Hg2+ compared to those of other metal ions can affect the efficiency of electron transfer and thereby result in their different response in fluorescence quenching towards N-CDs.
关键词： carbon dots,microreactor,Hg2+ detection,porous copper fibers
更新于2025-11-19 16:46:39
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New one-dimensional mercury(II) coordination polymers built up from dispiro-dipyridyloxy-cyclotriphosphazene: Structural, thermal and UV-vis absorption properties
摘要： Reactions of flexible polydendate ligand system dispiro-dipyridyloxy-cyclotriphosphazene (L) with a variety of mercury(II) salts (HgX2) (X= I￣, Cl￣) afforded two one-dimensional mercury(II) coordination polymers, namely formulated as {[Hg(L)(I)2]}n (1) and {[Hg(L)(Cl)2]}n.(ACN)0,341 (2). The isolated crystalline compounds were structurally characterized by elemental analysis and single crystal X-ray crystallography. The X-ray crystal structure analysis revealed that 1 and 2 crystallizes in the orthorhombic (space group Pccn) and the monoclinic crystal system (space group P21/c), in which L exhibited a κ2N coordination binding mode with the divalent Hg ions to form one-dimensional chain structures. The central Hg2+ ion in 1 and 2 has a distorted tetrahedral coordination geometry. UV-Vis properties and thermal stability of L and complexes (1, 2) were also investigated. UV-Vis experiments (titration and continuous variation (Job’s plot) analysis) showed that all of spectrophotometric properties in solution state supports crystal structure of complexes. According to TGA analysis, coordination polymers exhibited thermal stability up to 300 °C, but L showed more thermal stability than 1 and 2.
关键词： JOBS Diagram,Pyridyloxy Cyclotriphosphazene,Hg2+ Coordination Polymers,UV-Vis Absorption,1D Coordination Polymers
更新于2025-09-23 15:23:52
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A turn-on reactive fluorescent probe for Hg2+ in 100% aqueous solution
摘要： It is an effective and precise strategy to design the fluorescence probe for Hg2+ based on a new specific reaction. A novel turn-on fluorescent probe, 4-{2-[4-(2-Mercapto-benzoyloxy)-phenyl]-vinyl}-1-methyl-pyridinium[e]iodide (MBPVP) for Hg2+ was developed. The mechanism was based on Hg2+-mediated ester hydrolysis to release the fluorophore, 4-[2-(4-Hydroxy-phenyl)-vinyl]-1-methyl-pyridinium[e]iodide, which showed outstanding intramolecular charge transfer (ICT) and the yellow-green fluorescence were observed. The turn-on probe showed rapid response time, outstanding selectivity and sensitivity for Hg2+ over other metal ions in 100% PBS buffer (pH = 7.4). The linear range was 2-16 μM and the detection limit was 6.5 nM. Furthermore, MBPVP was used to determine Hg2+ in real samples and in the solid state.
关键词： Hg2+,ester hydrolysis,MBPVP,100% aqueous solution,fluorescent probe
更新于2025-09-23 15:23:52
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A Phosphonate Substituted Ruthenium(II) Bipyridyl Derivative as Photoelectrochemical Probe for Sensitive and Selective Detection of Mercury(II) in Biofluids
摘要： A ruthenium(II) bipyridyl derivative photoelectrochemical probe, Ru-1, is synthesized and coupled with TiO2 nanoparticles (Ru-1/TiO2) for the specific recognition and highly sensitive PEC detection of Hg2+ in a series of biofluids. The probe is designed with a chromophore, a thiocyanate recognition unit, a π-conjugated photoelectron transfer pathway, and a phosphonate anchor. TiO2 nanoparticles with strong affinity to phosphonate and suitable conduction band energy are used as intermediate layers to increase the Ru-1 adsorption amount and amplify the photocurrent response. Under irradiation, the Ru-1/TiO2/FTO with strong visible light harvesting capacity, aqueous stability and efficient photoelectron transfer, shows a high and stable photocurrent response. In the presence of Hg2+, however, the specific Hg2+ and NCS coordination changes the photophysical properties of Ru-1, imposing the probe with a wider band gap, a weaker absorbance, and a poorer photoelectron and hole separation efficiency, thus resulting in a significant photocurrent decrease. Based on the Hg2+ induced photocurrent change, the Ru-1/TiO2/FTO shows good selectivity and high sensitivity towards the PEC detection of Hg2+, with wide linear ranges from 10-12 to 10-7 and 10-7 to 10-3 g/mL, and a low limit of detection of 0.63 pg/mL. The PEC probe is recyclable and accurate for selective detection of Hg2+ in urine, serum and cell extracts. The whole analysis can be completed within 15 minutes. These good analytical performances indicate the PEC method might have great potential for the onsite detection of small molecules in bio-systems.
关键词： Hg2+ detection,photoelectrochemical probe,TiO2 nanoparticles,ruthenium(II) bipyridyl derivative,biofluids
更新于2025-09-23 15:21:21
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Inkjet-printed phosphorescent Iridium(III) complex based paper sensor for highly selective detection of Hg2+
摘要： First of its kind inkjet-printed phosphorescent Iridium(III) complex [Ir(TPQ)2(4-EO2-pic)] paper based chemosensor has been developed for Hg2+ ions. The probe is highly selective towards mercury analyte over other metal ions (Cu2+, Ca2+, Co2+, Cd2+, Pb2+, Zn2+, Ni2+, Mg2+, Mn2+, Al3+, Fe3+, La3+, Ag+, K+, Na+ and Li+). [Ir(TPQ)2(4-EO2-pic)] complex solution gave a visible color change from orange to yellow and significant phosphorescence quenching. Upon addition of aqueous Hg2+, the [Ir(TPQ)2(4-EO2-pic)] inkjet-printed paper gave a significant color change in both normal and UV light. The detection limit was found out as 1.78 × 10-8 M. Cyclic voltammetry (CV) studies were conducted to explore the further utility of [Ir(TPQ)2(4-EO2-pic)] as electrochemical sensor for Hg2+ ions in CH3CN / H2O (v/v = 1/1). The oxidation wave intensity of [Ir(TPQ)2(4-EO2-pic)] at 0.98 V decreased and new reversible oxidation wave was appeared at 0.91 V The binding ratio of the [Ir(TPQ)2(4-EO2-pic)]-Hg2+ complex was determined to be 1:1 according to the Job’s Plot. The probable binding modes of these [Ir(TPQ)2(4-EO2-pic)] with Hg2+ have also been suggested on the basis of the 1H-NMR titration, absorption and luminescence studies.
关键词： Phosphorescent,Iridium(III) complex,Inkjet-printed,Paper sensor,Hg2+ detection
更新于2025-09-23 15:21:21
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Dual-Emitting Quantum Dot Complex Nanoprobe for Ratiometric and Visual Detection of Hg2+ and Cu2+ ions
摘要： Herein we report the use of a dual emitting quantum dot complex (QDC; composed of blue emitting metal-methylsalicylaldimine complex being on the surface of orange emitting Mn2+-doped ZnS quantum dot) for ratiometric and visual detection of Hg2+ and Cu2+ ions - following the alterations in luminescence color, intensity ratio, chromaticity and hue of the QDC.
关键词： Hg2+ ions,Cu2+ ions,ratiometric detection,quantum dot complex,visual detection
更新于2025-09-23 15:21:01
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A dual colorimetric and near-infrared fluorescent turn-on probe for Hg2+ detection and its applications
摘要： The increasing Hg2+ contamination in environment and ecosystem has gained wide attention and thus demands for its facile and effective detection. In this study, we constructed a new fluorescent probe (E)-2-(2-(3-(1,3-dithian-2-yl)-4-hydroxystyryl)-4H-chromen-4-ylidene)malononitrile (DCM-Hg) for Hg2+ detection by incorporating the 1, 3-dithiane group to the dicyanomethylene-4H-pyran fluorophore for the first time. This probe can selectively detect Hg2+ via the Hg2+-triggered deprotection reaction of thioacetals, which leads to a distinct color change from purple to pink and obvious fluorescence enhancement in the near-infrared (NIR) region. The NIR fluorescence intensity increased linearly with Hg2+ level within the range from 0 to 100 μM and the detection limit of DCM-Hg for Hg2+ was found to be 6.8 × 10-8 mol/L. Moreover, the probe could sense Hg2+ on paper strips and image Hg2+ in living cells with low cytotoxicity, which demonstrates its potential application in environment and biological science.
关键词： Selectivity,Near-infrared,Imaging,Color change,Hg2+
更新于2025-09-23 15:21:01
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Double-Emission Ratiometric Fluorescent Sensors Composed of Rare-Earth-Doped ZnS Quantum Dots for Hg <sup>2+</sup> Detection
摘要： Quantum dots (QDs) are a class of zero-dimensional nanocrystal materials, whose lengths are limited to 2?10 nm. Their unique advantages such as wide excitation spectra, narrow emission spectra, and high quantum yield make their application possible in ?uorescence sensing, wherein QDs such as CdSe, CdTe, and CdS are used. Indeed, QDs have a wide range of applications in ?uorescence sensing, and there have been many reports of applications based on QDs as ion probes. The emission spectra of QDs can be adjusted by changing the size of the QDs or doping them with other ions/elements. However, the high toxicity of Cd and the poor anti-interference ability of single-emission ?uorescent probes greatly limit the applications of QDs in many ?elds. In this paper, ZnS QDs are doped with the rare-earth element Ce to form a low-toxicity double-emission ratiometric ?uorescent sensor, ZnS:Ce, for Hg2+ detection. The results of transmission electron microscopy (TEM), X-ray di?ractometry, X-ray photoelectron spectroscopy, and optical spectroscopy show that ZnS:Ce QDs were successfully synthesized. Under the optimal conditions, the concentration of Hg2+ was in the range of 10?100 μM, which had a linear relationship with the ?uorescence intensity of the ZnS:Ce QDs: the linear correlation coe?cient was 0.998, and the detection limit was 0.82 μM L?1. In addition, the ?uorescent sensor had good selectivity for Hg2+, and it was successfully applied to the detection of Hg2+ in laboratory water samples.
关键词： ZnS:Ce,Hg2+ detection,Quantum dots,ratiometric fluorescent sensor,double-emission
更新于2025-09-23 15:19:57