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A Low Power and Fast Tracking Light-to-Frequency Converter with Adaptive Power Scaling for Blood SpO2 Sensing
摘要： This paper presents a monolithic low power and fast tracking light-to-frequency converter for blood SpO2 sensing. Normally, the tracking speed and the power consumption are two contradictory characteristics. However different gain-bandwidth specifications for various ambient light intensities allow the dynamically optimization of the power consumption according to the light intensity. In this paper, the amplifier power consumption is adaptively scaled by the generated light-intensity-positively-correlated control voltage. Thus, the chip total power consumption at low light intensity is significantly decreased. Moreover, the proposed adaptive power scaling is achieved with a continuous analog domain, which does not introduce extra switching noise. The proposed light-to-frequency sensor chip is fabricated by using 0.35 μm CMOS technology with a die area of 1 × 0.9 mm2. The measurement results show that the pulse light response for any light intensity is no longer than two new output square-wave cycles. The maximum total current consumption is 1.9 mA from a 3.3 V supply voltage, which can be adaptively scaled down to only 0.7 mA if the output frequency is about 25 KHz or lower. The minimum operational supply voltage of the proposed sensor chip is 2.5 V in the temperature range of -25 to 80 oC with 4 KV ESD level (HBM).
关键词： light-to-frequency converter,low power,fast tracking,blood oxygen,biomedical sensor
更新于2025-09-23 15:23:52
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A CSRR-Based Sensor for Full Characterization of Magneto-Dielectric Materials
摘要： In this paper, a novel complementary split-ring resonator (CSRR)-based sensor for full characterization of magneto-dielectric materials is proposed. In general, the operation of microwave resonance-based sensor hinges on the shift in the resonance frequency and the change in the quality factor of the loaded structure. However, both the electric permittivity and the magnetic permeability of the material under test (MUT) have similar effect on the response of the sensor that makes the simultaneous determination of the permittivity and permeability challenging. To remove this difficulty, the main idea behind this paper is to localize the highest intensity of the electric and magnetic fields in two separate zones. By the analysis of the measured resonance frequency and quality factor, the real and imaginary parts of the electric permittivity and the magnetic permeability of the MUT can be determined. Although the characterization of the permittivity and permeability of materials using split-ring resonator and CSRR-based sensors has been widely used, to the best of our knowledge, the full characterization of magneto-dielectric materials using a single sensor has not yet been reported in this paper. As a proof of concept, the sensor was fabricated and used to measure the permittivity and permeability of several materials. Strong agreement between the extracted values and the reference data was achieved.
关键词： sensor,Complementary split ring resonator (CSRR),material characterization,split ring resonator (SRR),magneto-dielectric materials,permittivity and permeability
更新于2025-09-23 15:23:52
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[IEEE 2018 IEEE 7th International Conference on Photonics (ICP) - Kuah (2018.4.9-2018.4.11)] 2018 IEEE 7th International Conference on Photonics (ICP) - Differential Cross Spectrum Technique for Improving the Spatial Resolution of BOTDR Sensor
摘要： We propose a technique in BOTDR fiber sensor to generate a pair of pulsed probes via intensity modulation scheme for measuring distributed strain at high spatial resolution. The first probe consists of a long- and short duration of pulses separated by a short interval. The second probe only has the long pulse of the first probe. Introducing FFT in correlating the backscattered signals sampled by wide and narrow window functions for each probe gives narrow Brillouin spectrum width. The subtraction of the correlated signals obtained by the two probes results in high spatial resolution measurement. The intensity modulation makes it easier to generate the pair of pulsed probes having the same waveform of the long pulse and to obtain the results according to the measurement principle. We have achieved 0.2 m spatial resolution and 3.2 MHz Brillouin frequency accuracy in measuring a 350 m fiber.
关键词： BOTDR,spatial resolution,distributed fiber sensor,Brillouin frequency shift
更新于2025-09-23 15:23:52
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Surface Plasmon Resonance Based Highly Selective Fiber Optic Dopamine Sensor Fabricated Using Molecular Imprinted GNP/SnO <sub/>2</sub> Nanocomposite
摘要： Fabrication and characterization of a highly selective fiber optic surface plasmon resonance-based dopamine sensor using molecular imprinted graphene nanoplatelets/tin oxide (SnO2) nanocomposite have been reported. The synthesis of sensing layer has been carried out using a series of optimizations and morphological studies. The effectiveness of the sensing layer over other possible probe designs has been proved by performing control experiments for a dopamine concentration range covering the suggested level of dopamine for human being. The limit of detection (LOD) of the sensor evaluated is 0.031 μM, which is lower than the LOD values of various dopamine sensors fabricated using different methods. The specificity of the sensor for dopamine has been confirmed by performing experiments using various interferands while the stability and reusability of the sensor probe have been checked by performing experiments repeatedly for a long period of time. Apart from high sensitivity, low LOD, and fast response, the sensor can be used for remote sensing and online monitoring of dopamine.
关键词： surface plasmon resonance,SnO2 nanoparticles,optical fiber sensor,GNP/SnO2 nanocomposite,graphene,Dopamine,molecular imprinting
更新于2025-09-23 15:23:52
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Poly(azomethine-urethane) and zeolite-based composite: Fluorescent biosensor for DNA detection
摘要： In the present paper, a highly selective and sensitive fluorescent biosensor based on poly(azomethine-urethane) and zeolite for the determination of DNA molecules was developed. Zeolite was chosen to enhance with anionic or cationic functional groups in polymer matrix and interaction between polymer and DNA. Several parameters such as polymer concentration, pH and incubation time effect on the sensitivity of the fluorescent biosensor were optimized. Linear range was determined between 2.50 and 25.00 nmol/L DNA concentration and limit of detection (LOD) of the biosensor was calculated as 0.095 nmol/L under the optimal conditions. Interference study were also performed in the presence of different amino acids, cations and organic compounds. The results clearly indicated that the tested cations and compounds were not induced a significant fluorescence change and the proposed zeolite-based biosensor was shown a good selectivity for DNA.
关键词： fluorescent sensor,DNA,Zeolite,biosensor
更新于2025-09-23 15:23:52
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An automatic multi-thread image segmentation embedded system for surface plasmon resonance sensor
摘要： In order to reduce the uncertainties associated with manual selection of regions of interest (ROIs) commonly used in Surface Plasmon Resonance (SPR) imaging system, we proposed and implemented an automatic image segmentation method in an embedded system to facilitate the potential real-time applications. Intuitive marker-controlled watershed algorithm is developed to segment ROIs (reaction, blank, and background regions) from images acquired from an experimental image SPR system. The marker assignment algorithms and pre-processing algorithms are executed in parallel by multi-threading programming on the multi-core embedded system to both real-time and good quality of segmentation. This method exhibited a good robustness in a series of ROIs segmentation test. Furthermore, the intensity response from triplicate detection of glucose standard solutions indicated a good reproducibility of data. The linear range was from 2.5 mg/mL to 20.4 mg/mL, with a correlation coefficient (R2) of 0.999 and sensitivity of 2.69 a.u./mg/mL. In conclusion, the proposed automatic image segmentation method effectively makes the measurement more precise and simplified.
关键词： Optical sensor,Surface plasmon resonance (SPR),Biosensor,Watershed algorithm,Image segmentation
更新于2025-09-23 15:23:52
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Spectral analysis for photoacoustic pressure sensor designs: Theoretical model improvement and experimental validation
摘要： In the pulsed laser photoacoustic (PA) detection and spectroscopy applications, the fundamental frequency of the PA signal produced, and the sensor resonance frequency should be as close as possible to each other so that analyzes from the obtained signals can be performed effectively. In order to determine the fundamental frequency of the PA wave, a theoretical model approach based on the development of the frequency domain solution of the PA wave equation is presented for use in the PA pressure sensor designs. For the validation of the theoretical model approach, a PA experimental setup was established, and measurements were made in distilled water. The theoretical and experimental PA frequency spectra were determined to be very compatible with each other. Thus, the theoretical model approach was experimentally validated. According to the theoretical model approach, fundamental frequency values obtained from the experimental measurement results were determined with an average accuracy of ? 4.212%. Furthermore, it has been determined that this value has fallen to ?0.267% in the measurements. With the obtained results from the theoretical model approach, we propose that PA pressure sensors with the more selective and narrower band can be designed for more sensitive detection. Moreover, in this study the effects of different laser parameters such that pulse duration, and laser beam width, on the spectral content of the obtained PA signal are analyzed. These analyses will shed light on the vision of acoustic pressure sensor design by helping to select the most optimum parameters for PA detection.
关键词： Theoretical model approach,Photoacoustic wave equation,Acoustic pressure sensor,Frequency domain solution,Pulsed laser photoacoustic method,Spectroscopy
更新于2025-09-23 15:23:52
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Reduction and compensation of humidity measurement errors at cold temperatures using dual QCM humidity sensors based on graphene oxides
摘要： One of the difficulties in measurements of relative humidity in a variety of environments is temperature-dependence especially at cold temperatures. Here, we report on the reduction and the compensation of temperature effects on humidity measurements using dual humidity sensors based on quartz crystal microbalance (QCM). Graphene oxide film is coated on quartz crystals as a humidity sensing layer for the detection of water sorption by the change of resonance frequency. Relative humidity in a test chamber, where dual QCM humidity sensors are located, is precisely controlled using a humidity generator at the temperature range from 20 °C to ?60 °C. It is found that single QCM humidity sensors measure humidity significantly higher than reference relative humidity by the generator as temperature is lowered due to the temperature-dependent resonance of quartz crystals. In an attempt to cancel out the temperature-dependent oscillation of QCM sensors, the ratio of resonance frequencies of dual QCM humidity sensors is used. Consequently, temperature-dependent errors in humidity measurement at low temperatures are evidently reduced. For the compensation of the remaining errors in the humidity measurement by dual QCM humidity sensors, a single formula is empirically obtained. After the compensation of low temperature effects, the dual QCM humidity sensors provide the measurement capability in terms of residual errors less than 1.1%rh throughout temperatures from 20 °C to ?60 °C. This study provides a useful insight to extend the applicability of QCM-based humidity sensors to environments with cold temperatures.
关键词： Compensation,Graphene oxide,Cold temperature,Quartz crystal microbalance,Humidity measurement,Humidity sensor
更新于2025-09-23 15:23:52
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Triphenyl phosphate end-capped dicyanomethylene-4H-pyran as a near infrared fluorescent sensor for lysozyme in urine sample
摘要： A dicyano-methylene-4H-pyran (DCM)-based fluorescent probe DCPOP was designed for detecting lysozyme in urine sample. DCPOP showed obvious NIR emission (> 650 nm) avoiding the background fluorescence of urine (450 ? 600 nm). Compared to its mimic (DCPO), DCPOP has a big end-capped triphenyl phosphate (TPP) moiety, which induced good stability in several aqueous with different pH value. Furthermore, the end-capped TPP moiety showed weak interaction with lysozyme, which could modulate the emission signals of DCPOP. As a result, DCPOP could detect the lysozyme in both PBS buffer and real urine samples.
关键词： Fluorescent sensor,Near-infrared (NIR),Dicyano-methylene-4H-pyran-phenol (DCPO),Triphenyl phosphate end-cap,Lysozyme (Lys)
更新于2025-09-23 15:23:52
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The influences of temperature, humidity, and O2 on electrical properties of graphene FETs
摘要： The influences of temperature, humidity, and O2 to the gas sensing characteristics of graphene field effect transistors (FETs) have been studied as these environmental factors are often encountered in practical gas sensing applications. Both empirical results and theoretical analyses are characterized for heated graphene FET gas sensors from room temperature to 100°C under a wide range of applied gate voltages. It is found that at a constant applied gate voltage of -20 V with respect to the gate voltage at the neutrality point, the sensitivity of the device to humidity decreases; while the sensitivity to O2 decreases first, and increases afterwards as the operation temperature increases. These phenomena are explained by using the physisorption and chemisorption models between gases and the graphene surface. Furthermore, devices operate in the hole regime (the majority carrier is hole in the prototype devices) result in lower sensitivity to humidity and O2 as compared to those results of gas sensors operating in the electron regime due to the p-type doping effects of moisture and O2. As such, this work provides good foundations for graphene-based FET gas sensors in practical application environments under the influences of ambient air, temperature, and humidity.
关键词： ambient air,gas sensor,temperature,Graphene field effect transistor,humidity,oxygen
更新于2025-09-23 15:23:52