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- 实验方案
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The Antibody-Free Recognition of Cancer Cells Using Plasmonic Biosensor Platforms with the Anisotropic Resonant Metasurfaces
摘要: It is vital and promising for portable and disposable biosensing devices to achieve on-site detection and analysis of cancer cells. Although traditional labelling techniques provide an accurate quantitative measurement, the complicated cell staining and high-cost measurements limit its further development. Here, we demonstrate a non-immune biosensing technology. The plasmonic biosensors which is based on anisotropic resonant split ring resonators in terahertz range successfully realize the antibody-free recognition of cancer cells. The dependences of Δf and fitted phase slope (FPS) on the cancer cell concentration at different polarizations give new perspective in hexagonal radar maps. The results indicate that the lung cancer cell A549 and liver cancer cell HepG2 can be distinguished and determined simply based on the enclosed shapes in the radar maps without any antibody introduction. The minimum concentration of identification reduces as low as 1×104 cells/ml and such identification can be kept valid in a large range of cell concentration, ranging from 104 to 105. The construction of two-dimensional extinction intensity cards of corresponding cancer cells based on the wavelet transform method also supplies corresponding information for the antibody-free recognition and determination of two cancer cells. Our plasmonic MBs show a great potential in the determination and recognition of label-free cancer cells, being an alternative to non-immune biosensing technology.
关键词: terahertz,antibody-free biosensing,cancer cells,metasurfaces,continuous wavelet transform
更新于2025-09-23 15:19:57
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Special Issue: New Horizon of Plasmonics and Metamaterials
摘要: Plasmonics and metamaterials are growing fields that consistently produce new technologies for controlling electromagnetic waves. Many important advances in both fundamental knowledge and practical applications have been achieved in conjunction with a wide range of materials, structures and wavelengths, from the ultraviolet to the microwave regions of the spectrum. In addition to this remarkable progress across many different fields, much of this research shares many of the same underlying principles, and so significant synergy is expected. This Special Issue introduces the recent advances in plasmonics and metamaterials and discusses various applications, while addressing a wide range of topics in order to explore the new horizons emerging for such research.
关键词: metasurfaces,infrared sensors,plasmonics,metamaterials,polarization control
更新于2025-09-23 15:19:57
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Optical and Structural Phenomena at Multipulse Interference Femtosecond Laser Fabrication of Metasurfaces on a Thin Film of Amorphous Silicon
摘要: The formation of hexagonal microarrays of nanoholes (metasurfaces) in a 50-nm hydrogenated amorphous silicon film by means of three-beam interference of femtosecond laser pulses of the visible range (wavelength 515 nm) is studied experimentally with various exposures of the film. Characterization of arrays by scanning electron and optical microscopy, as well as optical transmission and reflection microspectroscopy, shows that an increase in the number of fixed energy laser pulses leads to a gradual evaporative formation of nanoholes in the film and, overall, the metasurface. Raman microspectroscopy reveals a simultaneous growth of the volume content of the crystal phase.
关键词: nanoholes,femtosecond laser,amorphous silicon,metasurfaces,interference
更新于2025-09-23 15:19:57
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Spina??Controlled Nonlinear Harmonic Generations from Plasmonic Metasurfaces Coupled to Intersubband Transitions
摘要: Metasurfaces that generate nonlinear optical responses provide new degrees of freedom for applications such as nonlinear holography, wave mixing, and new frequencies generation. To extend the utility of flat nonlinear optics, metasurfaces providing both giant nonlinear response for efficient frequency mixing in subwavelength films and a single-beam output with a local wavefront control need to be developed. Metasurfaces with giant nonlinear response have recently been realized using the concept of intersubband polaritons. Separately, nonlinear metasurfaces providing a single-beam nonlinear output with a local wavefront control have been studied. However, a metasurface platform that possesses both of these properties has yet to be demonstrated. Herein, the first such platform is presented and its operation for three- and four-wave mixing processes is demonstrated. This approach is based on using Pancharatnam–Berry phase control of local nonlinear response and on employing meta-atoms with specific symmetries to enable generation of only a single nonlinear beam. Experimentally, 400 nm-thick metasurfaces with a wavefront-controlled single-beam output are demonstrated for second- and third-harmonic generation at pump wavelength of approximately 10 μm. Power conversion efficiencies of 7.6 × 10?4% and 3.6 × 10?4% are obtained for the two nonlinear processes, respectively, at peak pumping intensity of only 80 kW cm?2.
关键词: nonlinear beam-steering,nonlinear optics,spin angular momentum,metasurfaces,intersubband transitions
更新于2025-09-23 15:19:57
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Deflecting transmissive light beams with metasurfaces based on crystalline silicon high-contrast grating
摘要: Dielectric metasurfaces have emerged and expanded rapidly for their success in realizing high-efficiency wavefront control in the optical and infrared ranges. However, devices have either been demonstrated at near-infrared regime using high-index semiconductors such as silicon, or they use lower index dielectric materials such as TiO2 or Si3N4 and operate in the visible wavelength regime to avoid the optical loss of dielectric materials. It seems that dielectric metasurfaces could not achieve either high index or high device efficiency, simultaneously. Here, we provide a crystalline silicon metasurface scheme to efficiently modulate transmitted light beams at the wavelengths as short as to 532 nm. The unit cell of the metasurfaces consists of high-contrast grating (HCG), which provides full 2π phase control for circular polarized incident beams in thin film. The demonstration of HCG deflector shows that the device enables high deflecting efficiency as high as those made by transparent materials. Our results provide a paradigm to functionalize transmitted light beams based on crystalline silicon in the visible wavelength regime.
关键词: dielectric metasurfaces,high-contrast grating,diffractive optics,crystalline silicon
更新于2025-09-23 15:19:57
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[IEEE 2018 Asia Pacific Magnetic Recording Conference (APMRC) - Shanghai, China (2018.11.15-2018.11.17)] 2018 Asia-Pacific Magnetic Recording Conference (APMRC) - Miniaturization for Dual-Beam Super-Resolution Optical Data Storage System with Ultra-High Capacities
摘要: A minimized optical lens head for dual-beam super-resolution optical storage system which is based on Stimulated Emission Depletion (STED)-like process with Petabyte data capacity is proposed. The whole bulky optical path is simplified to a customized metasurface with a diameter of 50 m, which generates a focused Gaussian beam and a donut beam overlapped perfectly in space. The specially designed lens head offers a distinct performance of chromatic aberration-free design with adaptability to multiple dual-beam combinations.
关键词: Optical Data Storage System,Metasurfaces,Super-resolution
更新于2025-09-19 17:15:36
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[IEEE 2018 IEEE International Symposium on Antennas and Propagation & USNC/URSI National Radio Science Meeting - Boston, MA, USA (2018.7.8-2018.7.13)] 2018 IEEE International Symposium on Antennas and Propagation & USNC/URSI National Radio Science Meeting - Characterization of Multiple-Layer Anisotropic Metasurfaces Based on Generalized Boundary Conditions
摘要: Scattering properties of multiple-layer anisotropic metasurfaces are characterized based on generalized boundary conditions. Once surface susceptibilities of all layers are determined, reflection and transmission coefficients could be readily derived for arbitrary incident angles and polarizations. The validity of this analytical method is demonstrated through comparison between computed results and full-wave simulations.
关键词: generalized boundary conditions,multiple-layer,anisotropic metasurfaces
更新于2025-09-19 17:15:36
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[IEEE 2018 18th Mediterranean Microwave Symposium (MMS) - Istanbul, Turkey (2018.10.31-2018.11.2)] 2018 18th Mediterranean Microwave Symposium (MMS) - Chiral SRR Metasurfaces for Circular Polarisation Conversion
摘要: A circular polarization dual band metamaterial polarization rotator composed of two double split ring resonators rotated 90o with respect to each other is presented. Asymmetric transmission between Txx and Tyy and symmetric transmission between Txy and Tyx has been achieved. The circular polarization is caused by the symmetric transmission between Txy and Tyx. The design has been demonstrated numerically at microwaves frequency. The structure holds promise for ultra-compact polarizing devices for any frequency range given the scalability of the approach.
关键词: Metasurfaces,Circular polarization,Chiral metamaterial,Split Ring Resonators
更新于2025-09-19 17:15:36
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Single-Layer Bifacial Metasurface: Full-Space Visible Light Control
摘要: Optical metasurfaces have attracted considerable attention thanks to their unprecedented ability to control the electromagnetic properties of light in subwavelength scale. These metasurface-integrated devices not only have the merit of compact form factor but also exhibit some better performance in comparison with conventional bulk optic devices. In this work, a novel metasurface that enables full-space light control is realized, offering an unconventional functionality that provides a new foothold for metasurface integration in optics. Multipolar interference and Pancharatnam–Berry phase are combined with each other and suggested as a physical background for the proposed device. As an example of the functionality, asymmetric beam steering and hologram generation are proposed and measured experimentally. As far as it is known, this is the first work achieving full-space control in visible range. Thanks to its manufactural ease and unprecedented function capability, this work will offer innovative potentials to be utilized in various integrated optic devices that need miniaturization or implementation of ingenious and light-weight optical components used in optical systems for photography, microscopy, computer vision, etc.
关键词: beam steering,metamaterials,multifunctional devices,holography,metasurfaces
更新于2025-09-19 17:15:36
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Wave diffraction by a half-screen with Nth order generalized sheet transition conditions
摘要: The scattering of plane waves by a half-plane with Nth order transition conditions is investigated. First of all, the reflection and transmission conditions of the transmissive surface are evaluated by using the generalized sheet transmission boundary conditions. The scattered geometrical optics fields are determined from the total geometrical optics and incident waves. The diffracted field is obtained by using a relation between the scattered geometrical optics and diffracted waves. The behaviors of the total, total geometric optics and diffracted fields are analyzed numerically.
关键词: Metasurfaces,Diffraction theory,Generalized sheet boundary conditions
更新于2025-09-19 17:15:36