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Zirconia Nanocolloids Having a Nanospace of Poly(cyclodextrin): Preparation and Application to Liquid Crystal Devices
摘要： Poly(β-cyclodextrin) (PβCyD)-protected ZrO2 nanocolloids were prepared by using a microwave reactor equipped with ultrasonic nozzle mixing at 240 °C for 30 min in a tetraethylene glycol solution of zirconium (IV) ethoxide in the presence of poly(β-cyclodextrin). Particles in PβCyD-protected ZrO2 nanocolloids have an average diameter of 7.2 nm and mainly distribute within the range of about 3 to 10 nm. The nanocolloids were dispersed in 4'-pentylbiphenyl-4-carbonitrile (5CB) and practical liquid crystal to construct novel twisted nematic liquid crystal devices (TN-LCDs). The response time of this TN-LCDs in the presence of PβCyD-protected ZrO2 nanocolloids was faster than that in the absence. The threshold voltage of TN-LCDs by doping PβCyD-protected ZrO2 nanocolloids decreased. The decrease of threshold voltage can reduce power consumption, which may meet the demands of future power-saving LCDs.
关键词： Twisted Nematic Liquid Crystal Devices,Zirconia Nanocolloids,Poly(cyclodextrin),Nanospace,4'-Pentylbiphenyl-4-Carbonitrile
更新于2025-09-23 15:22:29
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Advances in Colloid Science || Pretransitional Behavior and Dynamics in Liquid Crystal–Based Nanocolloids
摘要： The impact of nanoparticles on phase transitions in liquid crystal (LC)—nanoparticle nanocollids is still little known. This contribution results for dodecylcyanobiphenyl(12CB), pentylcyanobiphenyl (5CB), and hexyl isothiocyanatobiphenyl (6BT) as the LC host with the addition of BaTiO3 barium titanate barium titanate nanoparticles. The latter has a strong impact on the value of dielectric constant, relaxation time, and the discontinuity of the isotropic–mesophase transitions. The first-ever high-pressure studies in such systems are also presented.
关键词： dielectric constant,liquid crystals,nanocolloids
更新于2025-09-23 15:19:57
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Dual-functional supramolecular nanohybrids of quantum dot/biopolymer/chemotherapeutic drug for bioimaging and killing brain cancer cells in vitro
摘要： Glioblastoma (GBM) is the utmost aggressive and lethal primary brain cancer, which has a poor prognosis and remains virtually incurable. Nanomedicine with emerging disruptive nanotechnology alternatives, including designed supramolecular nanohybrids has excellent potential as multimodal tools against cancer by combining nanomaterials, biomacromolecules, and drugs. Thus, we developed and constructed for the first time quantum dot-biopolymer-drug nanohybrids based on host-guest chemistry for simultaneous bioimaging, targeting, and anti-cancer drug delivery against GBM cells in vitro. ZnS fluorescent quantum dots (ZnS-QDs) were produced using chemically modified polysaccharide, carboxymethylcellulose (CMC), as water-soluble capping ligand and biofunctional layer via a facile one-step eco-friendly aqueous colloidal process at room temperature and physiological pH. These hybrid inorganic-organic nanocolloids (ZnS@CMC) were electrostatically conjugated with doxorubicin (DOX) anti-cancer drug forming innovative supramolecular complexes (ZnS@CMC-DOX) for amalgamating bioimaging and killing cancer cells. These nanoconjugates were characterized regarding their optical and physicochemical properties combined with morphological and structural features. The cytocompatibility was evaluated by MTT assay using healthy and GBM cells. The results showed that ultra-small ZnS-QDs were expertly produced uniform nanocolloids (average size = 3.6 nm). They demonstrated photoluminescence emission within the visible range of spectra. The cell viability results in vitro showed no cytotoxicity of ZnS@CMC nanohybrids towards both cell types. In summary, the novelty of this research relies on using a nanotheranostic strategy for developing ZnS@CMC-DOX nanohybrids with supramolecular vesicle-like structures. They behaved simultaneously as active fluorescent nanoprobes and nanocarriers with modulated drug release for bioimaging and killing malignant glioma cells proving the high potential for applications in cancer nanomedicine.
关键词： Nanocarriers,Cancer nanotheranostic,Nanocolloids,Nanoconjugates,Fluorescent nanoparticles,Nanomedicine,Nanohybrids,Nanoparticles
更新于2025-09-12 10:27:22