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Identification of return of spontaneous circulation during cardiopulmonary resuscitation via pulse oximetry in a porcine animal cardiac arrest model
摘要： In this prospective study we investigated whether the pulse oximetry plethysmographic waveform (POP) could be used to identify return of spontaneous circulation (ROSC) during cardio-pulmonary resuscitation (CPR). Tweleve pigs (28 ± 2 kg) were randomly assigned to two groups: Group I (non-arrested with compressions) (n = 6); Group II (arrested with CPR and defibrillation) (n = 6). Hemodynamic parameters and POP were collected and analyzed. POP was analyzed using both a time domain method and a frequency domain method. In Group I, when compressions were carried out on subjects with a spontaneous circulation, a hybrid fluctuation or “envelope” phenomenon appeared in the time domain method and a “double” or “fusion” peak appeared in the frequency domain method. In Group II, after the period of ventricular fibrillation was induced, the POP waveform disappeared. With compressions, POP showed a regular compression wave. After defibrillation, ROSC, and continued compressions, a hybrid fluctuation or “envelope” phenomenon appeared in the time domain method and a “double” or “fusion” peak appeared in the frequency domain method, similar to Group I. Analysis of POP using the time and frequency domain methods could be used to identify ROSC during CPR.
关键词： Cardiopulmonary resuscitation,Cardiac arrest,Pulse oximetry plethysmographic waveform,Identification,Return of spontaneous circulation
更新于2025-09-10 09:29:36
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Comparison of oxygen saturation measured by pulse oximetry and arterial blood gas analysis in neonates
摘要： Background Arterial blood gas is usually beneficial to discern the nature of gas exchange disturbances, the effectiveness of compensation, and is required for adequate management. Although PaO2 is the standard measurement of blood oxygenation, oxygen saturation measured by pulse oximetry (SapO2) is now a customary noninvasive assessment of blood oxygenation in newborn infants. Objective To compare oxygen saturation measured by pulse oximetry (SapO2) and arterial blood gas (SaO2), its correlation with other variables, and to predict arterial partial pressure of oxygen (PaO2) based on SapO2 values. Methods A cross sectional study was conducted on all neonates admitted to Pediatric Intensive Care Unit (PICU) during February 2001 to May 2002. Neonates were excluded if they had impaired peripheral perfusion and/or congenital heart defects. Paired t-test was used to compare SapO2 with SaO2. Correlation between two quantitative data was performed using Pearson’s correlation. Regression analysis was used to predict PaO2 based on SapO2 values. Results Thirty neonates were included in this study. The difference between SaO2 and SapO2 was significant. There were significant positive correlations between heart rate /pulse rate and TCO2, HCO3; respiratory rate and TCO2, HCO3, base excess (BE); core temperature and HCO3, BE; surface temperature and pH, TCO2, HCO3, BE; SapO2 and pH, PaO2; and significant negative correlation between SapO2 and PaCO2; the correlations were weak. The linear regression equation to predict PaO2 based on SapO2 values was PaO2 = -79.828 + 1.912 SapO2. Conclusion Pulse oximetry could not be used in place of arterial blood gas analysis available for clinical purpose [Paediatr Indones 2003;43:211-215].
关键词： arterial oxygen saturation,pulse oximetry,arterial blood gas analysis,neonates
更新于2025-09-10 09:29:36
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Digital Pulse Oximetry for the Screeing of Lower Extremity Arterial Disease
摘要： The aim of the study was to investigate the usefulness of a handheld digital pulse oximetry in the detection of lower extremity arterial disease. A Retrospective study was performed in 45 patients with lower extremity arterial disease. We compared the accuracy of a handheld digital pulse oximetry and the ankle brachial index (ABI). Digital pulse oximetry was conducted for 42 patients with 84 limbs to measure the SaO2 of their index fingers and big toes in supine position. The ABI was defined as abnormal if it was less than 0.9. Pulse oximetry of big toes was defined as abnormal if the SPO2 was less than 96% or it was more than 2% lower than that of the index finger. Digital pulse oximetry had a sensitivity of 47%(95% CI, 34-60%) and specificity of 86%(95% CI, 64-96%). ABI had a sensitivity of 49%(95% CI, 34-64%) and specificity of 95%(95% CI, 72-99%). Positive predictive values were 91%(95% CI, 74-98%) for digital pulse oximetry and 96%(95% CI, 77-99%) for ABI. Negative predictive values were 37%(95% CI, 24-51%) for digitial pulse oximetry and 43%(95% CI, 25-72%) for ABI. In 22 cases with acute ischemicwere the sensitivity 73%, the specifity 100%, the positive predictive value 100% and the negative predictive value 79%. Handheld digital pulse oximetry of the big toes seems as accurate as ABI to detect lower extremity arterial diseases. The combination of both will help to distinguish low extremity arterial disease and spinal radiculopathy.
关键词： pulse oximetry,ankle brachial index,arterial disease
更新于2025-09-04 15:30:14