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In-Situ covalent synthesis of gold nanorods on GO surface as ultrasensitive Raman probe
摘要： In this paper, using thiolated graphene oxide (GO‐O‐SH) as substrate, gold nanorods (AuNRs) covalently linked to the GO surface by in‐situ seed growth method were first reported. The as‐prepared composites were characterized by UV–vis spectrum, transmission electron microscopy (TEM), scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT‐IR). Experimental results indicated that the introduction of short flexible organic chain between GO and AuNRs contributed to the homogenous synthesis of gold rods, and uniform gold nanorods with aspect ratio within 3~8 were covalently linked to the surface of GO with high stability and yield. The strategy represented an outstanding improvement in comparison to the traditional route for fabricating the two GO@AuNRs composites. Furthermore, based on coupling of nanomaterials, the composites could act as high sensitive Raman probe with limit of detection (LOD) reaching 1 × 10?12 M.
关键词： covalent synthesis,Raman probe,graphene oxide (GO),gold nanorods
更新于2025-09-23 15:23:52
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Raman spectroscopy and its use for live cell and tissue analysis
摘要： As research progresses in the field of life sciences, there is an increased demand for new technologies that can allow us to study intact cells and tissues. The quantitative analysis and mathematical modeling of living things based on empirical data is useful for connecting molecular biology to new areas, such as computational biology. Raman spectroscopy is regarded as one of the possible methods by which we can observe living organisms in a noninvasive manner. This could improve the quality of research in the field of medicine and health and will largely contribute to society in the future. The present review introduces some techniques based on Raman spectroscopy and evaluates their applications in intact live samples.
关键词： Raman probe,Raman spectroscopy,Biomedical,in vivo
更新于2025-09-23 15:22:29