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A Cross-sectional, Multi-center Study on Treatment of Facial Acne Scars With Low-Energy Double-Pass 1450-nm Diode Laser
摘要： Objective: Acne scars is the ultimate outcome of acne vulgaris, a prevalent skin disorder affecting the pilo-sebaceous unit. Laser resurfacing has been demonstrated to be an efficient therapy option for acne scars. Hence, we adopted this concept and conducted a study to evaluate the safety and efficacy of low-energy double-pass 1450-nm diode laser on acne scars. Methods: This study was conducted on forty-eight patients with acne scars, treated at 4-week interval with low-energy double-pass 1450-nm diode laser. Patients were evaluated clinically and with photographs, at day 0, 1st month and 3rd month post the final treatment and during follow-up visit. Results: Five treatment sessions were completed by all patients. Approximately 79.2% of patients showed around 30% improvement. At the end of 3rd month follow-up, 92.9% of the patients demonstrated >30% improvement. Vesicle formation was observed in two cases, with no post-inflammatory hyperpigmentation (PIH) and transient hyperpigmentation was observed in one case, which vanished within 2 months. Conclusion: Our study showed that 1450-nm diode laser treatment was efficient and well endured in facial acne scars when used with double-pass at low-energy.
关键词： Improvement,1450-nm diode laser,Facial acne scars,Low-energy double-pass
更新于2025-09-23 15:19:57
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Evaluation of the Safety and Efficacy of a Picosecond Alexandrite Laser With DLA for Acne Scars in Chinese Patients
摘要： Background and Objectives: Recently, picosecond laser treatment has been used as an effective treatment for acne scars. To evaluate the efficacy and safety of a picosecond alexandrite laser with a diffractive lens array in the treatment of acne scars in Chinese patients. Study Design/Materials and Methods: Patients with facial acne scars were treated with a picosecond alexandrite laser in three sessions at 4‐ to 6‐week intervals and followed up for 2 months. Primary outcomes were measured by physicians’ blinded evaluation of the acne scar using the ECCA (échelle d’éva physicians’luation clinique des cicatrices d’acné) grading scale. The secondary outcomes included the investigator global assessment (IGA) on the improvement of post‐inflammatory erythema (PIE), patients’ assessment of improvement on a 4‐point scale and of satisfaction on a 5‐point scale. Pain scores and adverse effects were also evaluated. Result: Twenty patients with Fitzpatrick skin types III and IV were enrolled in the study and completed all treatment and follow‐up visits. The mean ECCA scores fell from 197.75 ± 35.26 to 142.00 ± 35.92 (a 28% improvement), and the change was significant (P = 0.000). The mean IGA score of PIE improvement was 3.03 ± 0.75 (0 = no improvement and 4 = 76–100% improvement). On the basis of the patients’ self‐assessment, the average improvement scores were 2.30 ± 0.98 (0 indicating 0–25% improvement and 3 indicating >75% improvement). In total, 50% and 30% of the patients were “satisfied” and “very satisfied,” respectively, with the treatment. The mean pain score was 3.20 ± 0.50 (0 = no pain, 10 = maximum pain) with topical anesthesia. The adverse effects included transient and mild erythema, edema, and scabbing. Conclusions: Treatment with a picosecond alexandrite laser with a diffractive lens array is effective and safe for acne scars in Chinese patients. Lasers Surg. Med. ? 2019 Wiley Periodicals, Inc.
关键词： picosecond laser,post‐inflammatory erythema,alexandrite laser,acne scars,fractional laser
更新于2025-09-12 10:27:22
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Efficacy and Safety of Ablative Resurfacing With A High‐Energy 1,064 Nd‐YAG Picosecond‐domain Laser for the Treatment of Facial Acne Scars in Asians
摘要： Objectives: There have been few studies regarding the use of a picosecond‐domain laser for acne scars in Asians. This prospective study evaluated the efficacy and safety of a high‐energy 1,064 nm Nd:YAG picosecond‐domain laser for ablation and resurfacing of facial acne scars in Asians. Methods: Subjects were treated with a 1,064 nm picosecond laser (8 mm spot, 0.7–1.0 J/cm2, 5 Hz) every 4 weeks for three sessions. Two blinded dermatologists evaluated the pre‐ and 3‐month post‐treatment images with a 10‐point improvement scale. Subject pain, global improvement, and satisfaction were also assessed. The Facial Acne Scar Quality of Life (FASQoL) questionnaire was used to evaluate the subjects’ quality of life. Results: Twenty subjects aged 18–50 years with Fitzpatrick skin type III–V were enrolled. The median dermatologist‐rated improvement score was 3 out of 10. Subjects were satisfied to very satisfied with global improvement. Subjects’ quality of life significantly improved with a median FASQoL score of 10 after treatment compared with 21 before treatment (P < 0.001). Adverse effects were limited to erythema, pain, and edema without postinflammatory hyperpigmentation. Conclusions: The 1,064 nm picosecond‐domain laser with ablative resurfacing parameters is safe and effective for the treatment of acne scars in Asians. Lasers Surg. Med. ? 2019 Wiley Periodicals, Inc.
关键词： treatment,laser,picosecond,acne scars,fractionated
更新于2025-09-11 14:15:04
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The efficacy of fractional ablative carbon dioxide laser combined with other therapies in acne scars
摘要： Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO2 laser with a wavelength of 10,600 nm is commonly used in the field of cosmetology and clinical therapies for various skin diseases, and it can effectively improve skin regeneration and scar formation. To obtain satisfactory results for patients with scars, repetitive fractional laser therapy is always required; however, this treatment could easily lead to complications such as erythema, edema, infection, and post-inflammatory hyperpigmentation. In addition, different types of acne scars may have different responses to laser, further limiting its widespread use. In recent studies both home and abroad, a new pattern of fractional laser combined with other therapies to improve acne scar has been recommended to guarantee the safety and effective of treatment. This article reviews the recent pertinent literatures and summarized the progression of ablative fractional CO2 laser combined with other therapies on acne scar.
关键词： acne scars,combination therapy,fractional CO2 laser
更新于2025-09-11 14:15:04