BODIPY derivatives bearing borneol moieties: Enhancing cell membrane permeability for living cell imaging

摘要： Three novel boron-dipyrromethene (BODIPY) dyes bearing borneol moieties have been designed, synthesized and characterized. The single-crystal structure of the compound 3 was also elucidated for the first time. Their photophysical properties and confocal fluorescence images were investigated by the optical spectroscopy and Confocal fluorescence microscopy. The results indicate that the compounds 2-3 take on high fluorescence quantum yield and cell membrane permeability, which can be utilized as fluorescent visualizers for cell and lysosome fluorescence imaging.