- 标题
- 摘要
- 关键词
- 实验方案
- 产品
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A Nontoxic, Bio-friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System
摘要： A simple, nontoxic, bio-friendly, fluorescent chemodosimeter based on 2,4-dinitrobenzene and thio-rhodamine was designed and synthesized for the detection of toxic hypochlorite with high selectivity and sensitivity. First the oxidation property of the hypochlorite ion was applied on a hydrazide system (Ar (cid:0) NH (cid:0) N <). Practical utility of the sensor was proved through simple and fast visual detection of hypochlorite. Absorption and emission spectra exhibited the fast sensing capability of the sensor towards hypochlorite. The nontoxic, bio-friendly properties of the sensor in living cells increased its real time practical applicability as it was successfully applied for in-vitro detection of toxic hypochlorite in living cells.
关键词： living cell,Hypochlorite,nontoxic,chemodosimeter,fluorescent
更新于2025-09-10 09:29:36
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A Stable and Highly Sensitive Fluorescent Probe for Detection of Hypochlorite Ion <i>in vitro</i> and in Living Cells
摘要： We designed and synthesized 2-[(2-amino-5-nitro-phenylamino)-methyl]-5-diethylamino-phenol (L1) as a stable and highly sensitive hypochlorite probe. L1 may be used in both colorimetric and fluorometric applications, as well as in paper-strip detection for selective hypochlorite ion sensing. In this study, we successfully applied L1 to the imaging of local hypochlorite generation in the endosomes, including phagosomes, of living cells. Thus, L1 is an appropriate probe for the detection and visualization of hypochlorite ions in vitro and in living cells.
关键词： sensor,hypochlorite,endosome
更新于2025-09-10 09:29:36
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A cyclometalated iridium(III) complex-based fluorescence probe for hypochlorite detection and its application by test strips
摘要： A new cyclometalated iridium(III) complex-based fluorescence probe (IrCN) for hypochlorite (ClO?) has been synthesized and characterized. The probe displayed nonfluorescent around 577 nm, while a 54-fold enhancement in fluorescence emission intensity was observed after the addition of ClO? due to the removal of C=N isomerization effect. Such “turn-on” fluorescence probe worked excellently in wide pH range (5–12) with short response time (< 20 s) and the detection limit was as low as 0.11 μM. In addition, IrCN exhibited high selectivity even in the presence of other competing species. Furthermore, IrCN was successfully integrated in towards ClO? fluorescent test strips for real-time detection of ClO?.
关键词： Fluorescence probe,Iridium(III) complex,Test strips,Hypochlorite
更新于2025-09-09 09:28:46