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oe1(光电查) - 科学论文

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出版时间
  • 2018
研究主题
  • Photovoltaic power generation
  • Node load
  • Kendall rank correlation coefficient
  • Copula function
应用领域
  • Electrical Engineering and Automation
机构单位
  • State Grid Shanxi Electric Power Research Institute
  • Taiyuan University of Technology
36 条数据
?? 中文（中国） ▾

  • Prospective feasibility study for single-tracer sentinel node mapping by ICG (indocyanine green) fluorescence and OSNA (one-step nucleic acid amplification) assay in laparoscopic gastric cancer surgery

    摘要： Background The double-tracer method has been established for sentinel node (SN) mapping in gastric cancer surgery. However, there remain several unresolved issues that prevent its widespread use in clinical practice. In this study, we aimed to demonstrate the feasibility of single-tracer SN mapping in laparoscopic surgery for gastric cancer, using indocyanine green (ICG) fluorescence imaging with a one-step nucleic acid amplification (OSNA) assay intraoperatively. Methods Patients with clinical T1N0M0 gastric adenocarcinoma preoperatively were considered for inclusion if they had a single primary lesion 4 cm or less in maximal diameter. Immunohistochemical staining with the anti-cytokeratin 19 antibody was performed on preoperative biopsy specimens, and patients with faint positive reactions were excluded. Intraoperatively, single-tracer SN biopsy with ICG fluorescence imaging was performed, followed by laparoscopic gastrectomy with modified D1+ or D2 lymph node dissection. Results Twenty eligible patients underwent SN biopsy and laparoscopic gastrectomy. SNs were identified in 17 cases (85%), with a median number of three SNs per patient. The median times for SN mapping and OSNA assay were 19 and 35 min, respectively. OSNA assay detected one metastatic lymph node, but all other nodes were negative. No adverse effects were observed in relation to SN mapping. Conclusions Single-tracer SN mapping by ICG fluorescence imaging with intraoperative diagnosis by OSNA assay is feasible and safe. SNs can be identified in most patients, without producing false-negative results. Further clinical trial to demonstrate the sensitivity is ongoing.

    关键词： Fluorescence imaging,Indocyanine green,Sentinel lymph node,Surgical pathology,Gastric cancer

    更新于2025-09-23 15:23:52

  • [IEEE 2018 IEEE Conference on Antenna Measurements & Applications (CAMA) - Va?ster?s (2018.9.3-2018.9.6)] 2018 IEEE Conference on Antenna Measurements & Applications (CAMA) - Design of Low-profile Antenna with Multi-directional Beam

    摘要： An planar antenna having a low-pro?le structure using loop elements is proposed. The proposed antenna is vertically polarized and has four directional beams for sensor nodes. The thickness of the antenna is only 3.2 mm (0.11 effective wavelength) resulting in a low-pro?le structure. Simulated and measured average gain of 8.0 dBi and 5.6 dBi are obtained, respectively.

    关键词： wireless sensor network,sensor node,low-pro?le antenna,vertical polarization,multi-directional beam

    更新于2025-09-23 15:23:52

  • Paired-Agent Fluorescence Molecular Imaging of Sentinel Lymph Nodes Using Indocyanine Green as a Control Agent for Antibody-Based Targeted Agents

    摘要： Purpose. Paired-agent molecular imaging methods, which employ coadministration of an untargeted, “control” imaging agent with a targeted agent to correct for nonspecific uptake, have been demonstrated to detect 200 cancer cells in a mouse model of metastatic breast cancer. This study demonstrates that indocyanine green (ICG), which is approved for human use, is an ideal control agent for future paired-agent studies to facilitate eventual clinical translation. Methods. The kinetics of ICG were compared with a known ideal control imaging agent, IRDye-700DX-labeled antibody in both healthy and metastatic rat popliteal lymph nodes after coadministration, intradermally in the footpad. Results. The kinetics of ICG and antibody-based imaging agent in tumor-free rat lymph nodes demonstrated a strong correlation with each other (r = 0.98, p < 0.001) with a measured binding potential of -0.102 ± 0.03 at 20 min postagent injection, while the kinetics of ICG and targeted imaging agent shows significant separation in the metastatic lymph nodes. Conclusion. This study indicated a potential for microscopic sensitivity to cancer spread in sentinel lymph nodes using ICG as a control agent for antibody-based molecular imaging assays.

    关键词： Paired-agent imaging,Antibody-based targeted agents,Control agent,Indocyanine green,Fluorescence molecular imaging,Sentinel lymph node

    更新于2025-09-23 15:22:29

  • A Novel Multimodal NIR-II Nanoprobe for the Detection of Metastatic Lymph Nodes and Targeting Chemo-Photothermal Therapy in Oral Squamous Cell Carcinoma

    摘要： Current surgical treatment for oral squamous cell carcinoma (OSCC) must be as precise as possible to fully resect tumors and preserve functional tissues. Thus, it is urgent to develop efficient fluorescent probes to clearly identify tumor delineation, as well as metastatic lymph nodes. Chemo-photothermal therapy combination attracted a growing attention to increase anti-tumor effect in various types of cancer, including OSCC. In the present study, we designed a multimodal NIR-II probe that involves combining photothermal therapy with chemotherapy, imaging OSCC tumors and detecting metastatic lymph nodes. Methods: In this study, we synthesized a novel near infrared (NIR)-II probe named TQTPA [4,4'-((6,7-bis(4-(hexyloxy)phenyl)-[1,2,5]thiadiazolo[3,4-g]quinoxaline-4,9-diyl)bis(thiophene-5,2-diyl))bis(N,N-diphenylaniline)] via the Suzuki reaction and prepared multimodal nanoparticles (NPs) loading TQTPA and cis-dichlorodiammine platinum (CDDP) (HT@CDDP) by hyaluronic acid. The characteristics of the NPs, including their photothermal and imaging capabilities were investigated in vitro and in vivo. Their anti-tumor efficacy was evaluated using orthotopic, tongue tumor-bearing, nude mice. Results: The NPs possessed good stability and water solubility and were pH/hyaluronidase sensitive. The good tissue penetration quality and active targeting ability enabled the NPs to draw the outline of orthotopic tongue tumors and metastatic lymph nodes as small as 1 mm in nude mice by IR-808 under NIR exposure. In vitro and in vivo experiments validated the biocompatibility and low systematic toxicity of the NPs. At the same time, the NPs acted as multimodal therapy agents, combining photothermal therapy with chemotherapy. Conclusion: With a good imaging capability and anti-tumor efficacy, our NPs successfully outlined orthotopic tongue tumors and metastatic lymph nodes as well as enabled chemo-photothermal therapy combination. Our study established a solid foundation for the application of new clinical diagnosis and treatment patterns in the future.

    关键词： NIR-II imaging,metastatic lymph node detection,chemo-photothermal therapy,active targeting

    更新于2025-09-23 15:22:29

  • Eficacia de la imagen precoz con 68Ga-PSMA-I&T para la discriminación de lesiones en los pacientes con cáncer de próstata

    摘要： Objective: 68Ga-PSMA-uptake shows accumulation in the malignant lesions of prostate cancer patients as early as 5 min p.i. Studies indicate the value of adding an early image of the pelvis to the imaging protocol of 68Ga-PSMA-11 PET/CT scan showed contradictory results. In this study we planned to assess the significance of an additional early imaging in 68Ga-PSMA-I&T PET/CT imaging in prostate cancer patients. Materials and methods: A total of 35 prostate cancer patients referred to 68Ga-PSMA-I&T PET/CT imaging for restaging of the disease due to suspicion of relapse after definitive therapy were enrolled. First an early static pelvic image was obtained at a maximum of 300 s following injection of the radiotracer. Sixty minutes postinjection a whole-body PET/CT scan was conducted with an emission time of 3 min per bed position. The lesions which were categorized as local recurrence, bone lesion and lymph node metastasis in the early images, were compared with the late images in terms of number of lesions detected and SUVmax values. Results: 68Ga-PSMA-I&T PET/CT was positive in 23 of 35 patients (65.7%). A pathological uptake was observed in the prostatic bed site, in the pelvic lymph nodes, and in the bones in 17 patients (48.5%), 12 patients (34.2%), and 13 patients (37.1%), respectively. In one patient, focal pathological increased uptake in the prostatic bed with a SUVmax value of 5.8 was detected but this lesion disappeared in the late images. The average SUVmax values of the lesions in the prostatic bed were 13.7 ± 12.1 versus 26.3 ± 23.8 in the 5 min and 60 min studies respectively (p < 0.001). In one patient, the pathological uptake in the lymph node in the early study cleared in the late study, whereas in another accumulation of activity was detected in a pelvic lymph node in the late study, while there was no lymph node detected in the early study. The average SUVmax values of the lymph nodes were 12.1 ± 8.8 versus 26.3 ± 22.6 in the 5 min and 60 min studies respectively (p < 0.001). The average SUVmax values of the bone lesions were 11.4 ± 6.9 versus 15 ± 10.7 in the 5 min and 60 min studies respectively. Conclusion: Our study is the first in the literature to evaluate the impact of adding an early static pelvic image to the 68Ga-PSMA-I&T scan, in the detection rate of the lesions. Although there was no marked discordance between the 2 sets of images, the addition of an early image to the imaging protocol of 68Ga-PSMA-I&T scan would increase the efficacy of detection of malignant lesions in the pelvis, which might show rapid clearance and has the risk of being masked by the urinary system activity.

    关键词： Prostate-specific membrane antigen,68Ga-PSMA-I&T,PET/CT,Lymph node metastases,Prostate cancer

    更新于2025-09-23 15:22:29

  • Edge Computing Enabled Unmanned Module Defect Detection and Diagnosis System for Large-scale Photovoltaic Plants

    摘要： The network connectivity of sel?sh wireless networks (SeWNs) constituted by sel?sh nodes (SeNs) is investigated. The SeN’s degree of node-sel?shness (DeNS) is used for characterizing the effects of its energy resources and the bene?ts of the incentives provided for enhancing its transmission willingness. Furthermore, the SeNs’ signal to interference plus noise ratios are de?ned in terms of both their DeNSs and their interference factors. We then continue by quantifying the effect of node-sel?shness on the grade of network connectivity and derive both the upper and lower bounds of the critical DeNS. Explicitly, the network is deemed to be connected when the DeNS is below the lower bound and unconnected for a DeNS above the upper bound. This allows us to quantify the asymptotic critical DeNSs for our SeWNs. In addition, we develop an energy-conscious node-sel?shness model for characterizing the relationship between the SeN’s residual energy and its DeNS. Based on this model and on the asymptotic critical DeNS derived, the critical amount of residual energy required for maintaining a speci?c grade of network connectivity is determined, which is veri?ed by our simulation results.

    关键词： node-sel?shness,Network connectivity,energy resource,percolation theory,sel?sh wireless network

    更新于2025-09-23 15:21:01

  • Near-infrared fluorescence-guided surgery using indocyanine green facilitates secure infrapyloric lymph node dissection during laparoscopic distal gastrectomy

    摘要： Purpose We aimed to investigate the usefulness of near-infrared indocyanine green (ICG)-enhanced fluorescence guidance for infrapyloric LN dissection in laparoscopic distal gastrectomy. Methods This study enrolled patients with early gastric cancer scheduled for laparoscopic distal gastrectomy. After intra-operative submucosal injection of ICG (0.1 mg/mL), LN dissection was conducted under near-infrared ICG fluorescence guidance. The operation time, bleeding events during infrapyloric LN dissection were analyzed. Cases were retrospectively 1:3 propensity-score matched to patients who underwent laparoscopic distal gastrectomy without ICG injection. Results The mean time from midline omentectomy to exposure of the right gastroepiploic vein was significantly shorter in the ICG group (n = 20) than in the non-ICG group (n = 60) (13.05 ± 5.77 vs 18.68 ± 7.92 min; p = 0.001), and the incidence of bleeding during infrapyloric LN dissection was lower in the ICG group (20% vs 68.3%, p < 0.001). The two groups did not differ significantly regarding the number of LNs retrieved from the infrapyloric area (p = 0.434). Conclusions Near-infrared ICG fluorescence guidance facilitates safe and fast infrapyloric LN dissection in laparoscopic distal gastrectomy.

    关键词： Indocyanine green,Laparoscopic surgery,Lymph node dissection,Near-infrared imaging,Gastric cancer

    更新于2025-09-23 15:21:01

  • NIR Infrared imaging after peritumoral injection of indocyanine green to guide lymph node dissection in head and neck squamous cell carcinoma: A pilot feasibility study

    摘要： In head and neck squamous cell carcinoma (HNSCC), neck dissection is part of the surgical therapy. Beyond to the fact that radicality is a critical prognostic factor, this dissection could lead to significant morbidity, potentially avoidable when resected lymph nodes (LN) are proven to be non-invaded at pathology. Therefore, the definition of a method able to reliably identify the specific LN drainage area in HNSCC would represent a relevant progress, to better guide the neck dissection, potentially improving the radicality and reducing the morbidity. As near-infrared fluorescence imaging (NIR-FI) after indocyanine green (ICG) peritumoral injection has been validated as a sentinel procedure, we hypothesized that this approach could represent a new technique to identify the tumor-drainage area in HNSCC. We prospectively evaluated this technique in 14 patients with oral or oropharyngeal carcinoma scheduled for primary tumor resection and LN dissection. The trial was approved by the ethics committee of the Institut Jules Bordet (CE-2178) (EudraCT 2014-000298-37) and all patients signed informed consent before inclusion.

    关键词： Head and neck squamous cell carcinoma,Indocyanine green,Near-infrared fluorescence imaging,Lymph node dissection,Surgical guidance

    更新于2025-09-23 15:21:01

  • Directly photoexcited Dirac and Weyl fermions in ZrSiS and NbAs

    摘要： We report ultrafast optical measurements of the Dirac line-node semimetal ZrSiS and the Weyl semimetal NbAs, using mid-infrared pump photons from 86 meV to 500 meV to directly excite Dirac and Weyl fermions within the linearly dispersing bands. In NbAs, the photoexcited Weyl fermions initially form a non-thermal distribution, signi?ed by a brief spike in the differential re?ectivity whose sign is controlled by the relative energy of the pump and probe photons. In ZrSiS, electron-electron scattering rapidly thermalizes the electrons, and the spike is not observed. Subsequently, hot carriers in both materials cool within a few picoseconds. This cooling, as seen in the two materials’ differential re?ectivity, differs in sign, shape, and timescale. Nonetheless, we ?nd that it may be described in a simple model of thermal electrons, without free parameters. The electronic cooling in ZrSiS is particularly fast, which may make the material useful for optoelectronic applications.

    关键词： ultrafast optical measurements,electronic cooling,photoexcitation,Dirac line-node semimetal,thermalization,Weyl semimetal

    更新于2025-09-23 15:21:01

  • Functional-Link Neural Network for Nonlinear Equalizer in Coherent Optical Fiber Communications

    摘要： We propose and experimentally demonstrate a simple nonlinear equalizer based on functional-link neural network (FLNN). The nonlinear stochastic mapping enables FLNN to serve as a nonlinear network, so we construct an FLNN with the signals from the two polarizations and the mapped features as input to combat the fiber nonlinearity in coherent optical transmission systems. The FLNN can use the Moore-Penrose generalized inverse or the ridge regression to solve the weights, which can speed up the training process, and avoid the iterative and time-consuming training process that exist universally in most of the deep neural networks. We also extend the FLNN to the multi-channel transmissions. All of the received signals from different channels are stretched as the input and then we use a joint FLNN to extract features and equalize the nonlinear distortions. We conduct simulations and experiments to verify the proposed scheme. In the simulation and experiment, we transmit a 128 Gb/s polarization division multiplexed 16-QAM (PDM-16-QAM) signal over 1000-km and 600-km standard single mode fiber (SSMF), respectively. Both the simulation and experimental results show that the FLNN has similar performance as deep neural network (DNN), which can improve the transmission performance in the nonlinear region. Moreover, the FLNN can avoid the gradient dissipation and local minimum problems in DNN, which simplify the training process. We also extend the proposed scheme in a five-channel (5 × 160 Gb/s) multiplexed transmission system. In simulation, we use joint FLNN and joint DNN to compensate the nonlinear distortions, respectively. We find that the BERs of the five channels can be below 7% HD-FEC with nonlinear equalizer.

    关键词： enhancement node,functional-link neural network,Optical communication,deep neural network,fiber nonlinearity

    更新于2025-09-23 15:19:57