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Note: Complementary approach for radiation dosimetry with Ag <sup>+</sup> -activated phosphate glass
摘要: Silver ion-activated phosphate glass (Ag+-glass) has a good potential for application to radiation dosimetry in various radiation fields due to its multifunctional properties as a detector. The Ag+-glass provides three independent signals of radiophotoluminescence, optical absorption, and nuclear track. The combination of these signals allows the dynamic range of the measured dose (10 μGy–10 kGy) and linear energy transfer (<10 keV/μm and >1 MeV/μm) to be widened.
关键词: optical absorption,radiophotoluminescence,Ag+-activated phosphate glass,radiation dosimetry,nuclear track
更新于2025-09-23 15:21:01
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Three-dimensional radiation dosimetry based on optically-stimulated luminescence
摘要: A new approach to three-dimensional (3D) dosimetry based on optically-stimulated luminescence (OSL) is presented. By embedding OSL-active particles into a transparent silicone matrix (PDMS), the well-established dosimetric properties of an OSL material are exploited in a 3D-OSL dosimeter. By investigating prototype dosimeters in standard cuvettes in combination with small test samples for OSL readers, it is shown that a sufficient transparency of the 3D-OSL material can be combined with an OSL response giving an estimated >10.000 detected photons in 1 second per 1mm3 voxel of the dosimeter at a dose of 1 Gy. The dose distribution in the 3D-OSL dosimeters can be directly read out optically without the need for subsequent reconstruction by computational inversion algorithms. The dosimeters carry the advantages known from personal-dosimetry use of OSL: the dose distribution following irradiation can be stored with minimal fading for extended periods of time, and dosimeters are reusable as they can be reset, e.g. by an intense (bleaching) light field.
关键词: optically-stimulated luminescence,silicone matrix,OSL,three-dimensional dosimetry,radiation dosimetry
更新于2025-09-23 15:19:57
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Dual-Color Plasmonic Nanosensor for Radiation Dosimetry
摘要: Radiation dosimeters are critical for accurately assessing the levels of radiation exposure of tumor sites and surrounding tissues and for optimizing therapeutic interventions as well as for monitoring environmental exposure. To fill the need for a simple, user-friendly and inexpensive dosimeter, we designed an innovative colorimetric nanosensor-based assay for detecting ionizing radiation. We show that hydroxyl radicals generated by ionizing radiation can be used to etch gold nanorods (AuNRs) and silver nanoprisms (AgNPRs), yielding reproducible color changes for radiation dose detection in the range of 50-2000 Rad, broad enough to cover doses used in hyperfractionated, conventional, and hypofractionated radiotherapy. This range of doses detected by this assay correlates with radiation induced DNA damage response in mammalian cells. Furthermore, this AuNR- and AgNPR-based sensing platform has been established in a paper format that can be readily adopted for a wide range of applications and translation.
关键词: Radiation dosimetry,gold nanorods,silver nanoprisms,dual-color nanosensor,colorimetric detection
更新于2025-09-23 15:19:57
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Radio-Fluorogenic Gel Dosimetry with Coumarin
摘要: Gel dosimeters are attractive detectors for radiation therapy, with properties similar to biological tissue and the potential to visualize volumetric dose distributions. Radio-fluorogenesis is the yield of fluorescent chemical products in response to energy deposition from ionizing radiation. This report shares the development of a novel radio-fluorogenic gel (RFG) dosimeter, gelatin infused with coumarin-3-carboxlyic acid (C3CA), for the quantification of imparted energy. Aqueous solutions exposed to ionizing radiation result in the production of hydroxyl free radicals through water radiolysis. Interactions between hydroxyl free radicals and coumarin-3-carboxylic acid produce a fluorescent product. 7-hydroxy-coumarin-3-carboxylic acid has a blue (445 nm) emission following ultra-violet (UV) to near UV (365–405 nm) excitation. Effects of C3CA concentration and pH buffers were investigated. The response of the RFG was explored with respect to strength, type, and exposure rate of high-energy radiation. Results show a linear dose response relationship independent of energy and type, with a dose-rate dependency. This report demonstrates increased photo-yield with high pH and the utility of gelatin-RFG for phantom studies of radiation dosimetry.
关键词: radio-fluorogenic gel,luminescent dosimetry,radiation dosimetry,gel dosimetry
更新于2025-09-04 15:30:14
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Effect of Co-activation on the Thermoluminescence and Photoluminescence Properties of Nano-crystalline K2Ca2(SO4)3:Eu,Cu
摘要: The effect of co-doping and change in dopant concentration on thermoluminescence (TL) properties of K2Ca2(SO4)3:Eu,Cu has been studied by varying the concentration of the two dopants europium and copper (0.05, 0.10, 0.20, 0.30 and 0.40 mol % equally divided between Eu and Cu). Chemical co-precipitation technique was used to prepare the co-doped phosphor K2Ca2(SO4)3:Eu,Cu. Using Williamson-Hall plot in the X-ray diffraction pattern of the phosphor, the size of the crystallites was estimated to be around 51.3-73.6 nm. Maximum TL sensitivity was obtained for 0.2 mol% concentration (0.1 mol% Eu and 0.1 mol% Cu). The co-doped phosphor was compared for its TL sensitivity with that of the singly doped phosphors K2Ca2(SO4)3:Eu, and K2Ca2(SO4)3:Cu and the standard TL dosimeter LIF:Mg, Ti (TLD-100). Higher TL peak intensity of co-doped phosphor compared to the singly doped phosphors K2Ca2(SO4)3:Eu and K2Ca2(SO4)3:Cu has been explained on the basis of energy transfer between the dopants. Photoluminescence studies of the co-doped and the singly doped samples confirm a positive energy transfer from Cu2+ to Eu2+. A linear TL response curve over a wide range of doses (10 Gy to 1 kGy) is a key factor that makes the present phosphor quite capable for dosimetric purposes.
关键词: radiation dosimetry,up-conversion,nanophosphor,photoluminescence,thermoluminescence
更新于2025-09-04 15:30:14
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Effect of Er3+ on NaSrB glass: thermoluminescence and structural analysis
摘要: The present work reports the investigations on Er3+-doped sodium–strontium–borate glasses for their structural, optical and thermoluminescence (TL) properties. While the amorphous nature of the prepared glasses is confirmed by the powdered X-ray diffraction (XRD), some interesting features were found in the structure and Fourier-transform infrared (FTIR) studies such as the nanocrystallization and the presence of BO3 and BO4 structural units. Some physical parameters such as ion concentration, polaron radius, inter-nuclear distance, and field strength are calculated and analyzed. Optical band gap was found to be sensitive to the concentration of the dopants. TL glow curve exhibits a single peak but it shifts with variation in concentration of Er2O3. Calculation of kinetic parameters show that the prepared glasses exhibit second-order kinetics. The effective atomic number (Zeff) of prepared glasses is also calculated which indicates their suitability for application in radiation dosimetry.
关键词: thermoluminescence,sodium–strontium–borate glasses,optical properties,radiation dosimetry,Er3+-doped,structural analysis
更新于2025-09-04 15:30:14