- 标题
- 摘要
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- 实验方案
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Photo‐controlled Dopamine Polymerization on DNA Origami with low Nanometer Resolution
摘要： Temporal and spatial control over polydopamine formation on the nanoscale can be achieved by installing an irradiation-sensitive polymerization system on DNA origami. Precisely distributed G-quadruplex structures on the DNA template serve as anchors for embedding the photosensitizer protoporphyrin IX, which — upon the irradiation with visible light — induces a multistep oxidation from dopamine to polydopamine, producing polymeric structures on designated areas within the origami framework. The photochemical polymerization process allows the exclusive control over polydopamine layer formation, which is adjusted by simply switching the light source on and off. The obtained polymer–DNA hybrid material shows significantly enhanced stability properties paving the way for biomedical and chemical applications that are commonly prohibited by the sensitivity of DNA.
关键词： DNA origami,DNA nanotubes,Photopolymerization,Polydopamine,Stability in water
更新于2025-09-11 14:15:04
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Photo-controlled Dopamine Polymerization on DNA Origami with low Nanometer Resolution
摘要： Temporal and spatial control over polydopamine formation on the nanoscale can be achieved by installing an irradiation-sensitive polymerization system on DNA origami. Precisely distributed G-quadruplex structures on the DNA template serve as anchors for embedding the photosensitizer protoporphyrin IX, which — upon the irradiation with visible light — induces a multistep oxidation from dopamine to polydopamine, producing polymeric structures on designated areas within the origami framework. The photochemical polymerization process allows the exclusive control over polydopamine layer formation, which is adjusted by simply switching the light source on and off. The obtained polymer–DNA hybrid material shows significantly enhanced stability properties paving the way for biomedical and chemical applications that are commonly prohibited by the sensitivity of DNA.
关键词： DNA origami,DNA nanotubes,Photopolymerization,Polydopamine,Stability in water
更新于2025-09-11 14:15:04