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Influence of Axial Length on Thickness Measurements Using Spectral-Domain Optical Coherence Tomography
摘要： The purpose of this study was to assess the in?uence of axial length on spectral-domain optical coherence tomography (SD-OCT) thickness measurements in patients with subretinal visual implants. Data from eight emmetropic pseudophakic eyes of eight patients with subretinal visual implants were analyzed retrospectively. These patients participated in the monocentric part of a multicenter trial. The axial length was measured in three short (<22.5 mm), three medium (22.51–25.50 mm), and two long (>25.52 mm) eyes. Using Heidelberg Spectralis, the known thickness of a subretinal implant microchip (70 lm) was measured on 15 images per eye with SD-OCT, using the software calipers. The mean axial length was 20.8 6 0.8 mm in short eyes, 23.3 6 0.4 mm in medium eyes, and 26.3 6 0.5 mm in long eyes. We found in short eyes, in medium eyes, and in long eyes a mean value of microchip thickness measurements from SD-OCT of 82.9 6 1.4 lm, 70.5 6 1.3 lm, and 64.2 6 1.3 lm, respectively. The thickness measurements decreased in SD-OCT measurements with longer axial lengths signi?cantly (P < 0.0001). Axial length in?uences SD-OCT thickness measurements. Our ?ndings demonstrate accuracy of the scaling in SD-OCT thickness measurements in emmetropic medium eyes. Caution is recommended when comparing the measured values of short and long eyes with the normative database of the instrument. There is a need for larger sample-size studies to con?rm our results.
关键词： subretinal visual implant,spectral-domain optical coherence tomography (SD-OCT),axial length,Heidelberg Spectralis,in vivo measurement
更新于2025-09-23 15:21:01
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[Advances in Intelligent Systems and Computing] Intelligent Computing Volume 857 (Proceedings of the 2018 Computing Conference, Volume 2) || Automated Inner Limiting Membrane Segmentation in OCT Retinal Images for Glaucoma Detection
摘要： This paper proposes an automated algorithm to segment inner limiting membrane, i.e., the top most retinal layer in spectral domain optical coherence tomography (SD-OCT) scan. Its segmentation enables ophthalmologist to diagnose retinal diseases like macular edema and glaucoma as they affect ILM layer. The foremost purpose behind this segmentation is to correctly detect and diagnose glaucoma. Glaucoma is declared as the second common cause of blindness by World Health Organization, and can cause severe damage if not treated earlier. Optic-nerve-head (ONH) centered OCT scans are considered for glaucoma. Glaucoma can be described as cupping of optic nerve head, i.e. increase in the diameter of optic cup, and ends up in increasing cup to disc diameters (CDR) ratio. ILM is steeper in central-cup section in glaucoma images than normal images. Therefore, ILM is used to extract cup from macula or ONH centered OCT image volumes and then classify them further as glaucoma-tic or normal eye.
关键词： Cup to disc diameters (CDR),Spectral domain optical coherence tomography (SD-OCT),ILM,Segmentation,Glaucoma
更新于2025-09-10 09:29:36
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A Case of Acute Bilateral Solar Retinopathy Diagnosed with Spectral Domain Optical Coherence Tomography
摘要： To report a case of acute bilateral solar retinopathy diagnosed using spectral domain optical coherence tomography (SD-OCT). Case summary: A 74-year-old female patient consulted for amblyopia and metamorphopsia at a local hospital. On the patient’s first visit, there were no abnormal findings based on slit lamp microscope. Additional examinations were conducted since the patient complained of metamorphopsia with visual acuity and corrected vision. Fundus photography and SD-OCT examination showed symmetrical lesions near the bilateral macula. Several evaluations of the patient’s medical history confirmed that the patient was exposed directly to the sun for 30 minutes. One month after the first visit, visual acuity improved but metamorphopsia remained unchanged. Lesion status could not be confirmed by fundus photography. There was no abnormal finding on fluorescence angiography. SD-OCT examination still showed bilateral symmetric disruption of the outer retina but with no significant interval change. Conclusions: In the present case, the patient with bilateral intraocular lenses who complained of acute binocular amblyopia was diagnosed accurately through SD-OCT tests for bilateral symmetric disruption on the outer retina and repetitive evaluations of patient’s medical history.
关键词： Spectral domain optical coherence tomography (SD-OCT),Acute bilateral solar retinopathy,Patient’s medical history,Disruption
更新于2025-09-04 15:30:14