- 标题
- 摘要
- 关键词
- 实验方案
- 产品
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Design of Magnetica??Plasmonic Nanoparticle Assemblies via Interface Engineering of Plasmonic Shells for Targeted Cancer Cell Imaging and Separation
摘要： Magnetic-plasmonic nanoparticles have received considerable attention for widespread applications. These nanoparticles (NPs) exhibiting surface-enhanced Raman scattering (SERS) activities are developed due to their potential in bio-sensing applicable in non-destructive and sensitive analysis with target-specific separation. However, it is challenging to synthesize these NPs that simultaneously exhibit low remanence, maximized magnetic content, plasmonic coverage with abundant hotspots, and structural uniformity. Here, a method that involves the conjugation of a magnetic template with gold seeds via chemical binding and seed-mediated growth is proposed, with the objective of obtaining plasmonic nanostructures with abundant hotspots on a magnetic template. To obtain a clean surface for directly functionalizing ligands and enhancing the Raman intensity, an additional growth step of gold (Au) and/or silver (Ag) atoms is proposed after modifying the Raman molecules on the as-prepared magnetic-plasmonic nanoparticles. Importantly, one-sided silver growth occurred in an environment where gold facets are blocked by Raman molecules; otherwise, the gold growth is layer-by-layer. Moreover, simultaneous reduction by gold and silver ions allowed for the formation of a uniform bimetallic layer. The enhancement factor of the nanoparticles with a bimetallic layer is approximately 107. The SERS probes functionalized cyclic peptides are employed for targeted cancer-cell imaging and separation.
关键词： cell separation,surface-enhanced Raman scattering,bio-sensing,magnetic-plasmonic nanoparticles,cancer-cell imaging
更新于2025-09-23 15:19:57
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Wireless Sensor Chip Platform Using On-Chip Electrochromic Micro Display
摘要： In this paper, a proof-of-concept sensor platform for an all-in-one wireless bio sensor chip was developed and evaluated. An on-chip battery, an on-chip electrochromic display (ECD), a micro processor, a voltage converter and analog switches were implemented on a printed circuit board. Instead of bio-sensor, a temperature sensor was used to evaluate the functionality of the platform. The platform successfully worked in an electrolyte and the encoded measurement result was displayed on the ECD. The displayed data was captured by a CMOS digital camera and the measured data could be successfully decoded by a computer program.
关键词： disposable bio-sensing chip,on-chip electrochromic display,on-chip battery
更新于2025-09-19 17:15:36
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Graphene-TMD Van der Waals Heterostucture Plasmonics
摘要： The collective excitations of electrons in the bulk or at the surface, viz. plasmons, play an important role in the properties of materials, and have generated the field of “plasmonics”. We report the observation of a highly unusual plasmon mode on the surface of Van der Waals heterostructures (vdWHs) of graphene monolayer on 2D transition metal dichalcogenide (Gr-TMD) substrate. Since the exponentially decaying fields of surface plasmon wave propagating along interface is highly sensitive to the ambient refractive index variations, such heterostructures are useful for ultra-sensitive bio-sensing.
关键词： Van der Waals heterostructures,Bio-sensing,Surface plasmon
更新于2025-09-19 17:13:59
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Exfoliation behavior of van der Waals strings: case study of Bi <sub/>2</sub> S <sub/>3</sub>
摘要： The family of crystals constituting covalently bound strings, held together by van der Waals forces, can be exfoliated into smaller entities, similar to crystals made of van der Waals sheets. Depending on the anisotropy of such crystals, and the spacing between their strings in each direction, van der Waals sheets or ribbons can be obtained after the exfoliation process. In this work, we demonstrate that ultra-thin nanoribbons of bismuth sulfide (Bi2S3) can be synthesized via a high power sonication process. The thickness and width of these ribbons are governed by the van der Waals spacings around the strings within the parent crystal. The lengths of the nanoribbons are initially limited by the dimensions of the starting bulk particles. Interestingly, these nanoribbons change stoichiometry, composition and are elongated when the duration of agitation increases, due to Ostwald ripening. An application of the exfoliated van der Waals strings is presented for optical biosensing using photoluminescence of Bi2S3 nanoribbons, reaching detection limits of less than 10 nM L-1 in response to bovine serum albumin. The concept of exfoliating van der Waals strings could be extended to a large class of crystals for creating bodies ranging from sheets to strings, with optoelectronic properties different from that of their bulk counterparts.
关键词： bio-sensing,photo luminescence,van der Waals strings,bismuth sulfide,liquid phase exfoliation,Bi2S3,Ostwald ripening
更新于2025-09-10 09:29:36
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[ASME ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference - Boston, Massachusetts, USA (Sunday 2 August 2015)] Volume 3: 17th International Conference on Advanced Vehicle Technologies; 12th International Conference on Design Education; 8th Frontiers in Biomedical Devices - Low-Cost Label-Free Bio-Detection System Using Double-Sided Grating Waveguide Couplers
摘要： Low-cost label-free bio-sensing systems have long been desired to enable rapid, sensitive, quantitative, and high-throughput biosensing and chemical applications. Here we present an optical bio-detection system consists of injection-molded biosensors based on double-sided grating waveguide couplers and an optical intensity-based detection platform for low-cost, real-time, and label-free bio-sensing. The biosensors were fabricated combining injection-molding and sputtering techniques, providing unique advantages of low-cost and reduced production time. A simple and cost-effective optical intensity-based detection system employing a low-cost light emitting diode and a simple photodetector is also developed to perform label-free bio-sensing. We demonstrate that a high refractive index resolution of 6.43 x 10^-5 RIU is achieved with this compact bio-sensing system, showing great promises for low-cost, real-time, label-free detection in bio-medical and chemical applications.
关键词： label-free bio-sensing,double-sided grating waveguide couplers,optical bio-detection system,optical intensity-based detection,injection-molded biosensors
更新于2025-09-09 09:28:46