摘要： Introduction: We sought to update our experience of oncologic and functional outcomes of robot-assisted radical prostatectomy (RARP) for prostate cancer in patients with history of holmium laser enucleation of the prostate (HoLEP). Methods: 27 patients with previous HoLEP who underwent RARP were matched 1:1 to RARP patients with no history of transurethral surgery. Demographic, operative, oncologic, continence, and erectile function outcomes were analyzed. Results: Median time between HoLEP and RARP was 31 months with a mean PSA doubling time of 4.28 ng/mL/yr. Operative times were significantly longer with higher bladder neck reconstruction rates and similarly low complication rates. Biochemical recurrence was relatively low (7%) in HoLEP group, identical to the comparative group. Continence at last follow up was not statistically significant between groups although time to continence favored the non-HoLEP cohort. Erectile function recovery was generally poor in the post HoLEP cohort (11%) although bilateral nerve sparing was rarely performed (11%). Compared to our initial experience, there were significant improvements in time to continence (16 vs 36 weeks). No T2 post-HoLEP RARP since 2010 has had a positive surgical margin. Conclusions: Post HoLEP prostatectomy remains feasible with similar perioperative and oncologic outcomes compared with matched cohorts. Functional recovery remains slowed yet may continue to improve with technical familiarity.