研究目的
To discuss the principles, applications, and limitations of Positron Emission Tomography (PET) in clinical and research settings.
研究成果
PET is a powerful imaging modality with high sensitivity and spatial resolution, useful in oncology, cardiology, and neurology. Despite its advantages, the high cost and technical requirements limit its accessibility.
研究不足
The spatial resolution of PET is limited by the number and size of the detectors, noncollinearities of the 2γ-emission process, and by the straggling length of the positrons. The requirement for an on-site cyclotron and the short half-life of radiopharmaceuticals add to the complexity and cost.
1：Experimental Design and Method Selection:
The chapter discusses the basic principles of PET, including the annihilation of positrons and electrons, detection of γ-photons, and the use of scintillation counters for imaging.
2：Sample Selection and Data Sources:
The use of radiopharmaceuticals containing β+-emitters for internal administration is described, with a focus on isotopes like C-11, N-13, O-15, and F-
3：List of Experimental Equipment and Materials:
PET scanners, scintillation detectors (e.g., BGO, LSO, LYSO, GSO), and radiopharmaceuticals are mentioned.
4：Experimental Procedures and Operational Workflow:
The process from isotope production to image processing is outlined, including the synthesis of PET tracers and the detection of γ-photons.
5：Data Analysis Methods:
Coincidence detection schemes and tomographic image formation are discussed.
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