摘要： Two-dimensional (2D) anisotropic transport of photons/electrons is crucial for constructing ultracompact on-chip circuits. To date, the photons in organic 2D crystals usually exhibit the isotropic propagation, and the anisotropic behaviors have not yet been fully demonstrated. Herein, an orientation-controlled photon-dipole interaction strategy was proposed to rationally realize the anisotropic and isotropic 2D photon transmissions in two self-assembled cocrystal polymorph microplates. The monoclinic microplate adopting a nearly horizontal molecular transition dipole orientation in the 2D plane, exhibits anisotropic photon-dipole interactions and thus distinct re-absorption waveguide losses for different 2D directions. By contrast, the triclinic microplate with a vertical transition dipole orientation, shows the 2D isotropic photon-dipole interactions and thus the same re-absorption losses along different directions. Based on the anisotropic transport mechanism, a directional signal outcoupler (DSO) was further designed for the high-fidelity transmission of the real signals, which would enlighten the development of 2D anisotropic optical devices.