研究目的
To compare a thulium-doped fiber laser (TDFL) emitting a wavelength of 1940 nm and a diode laser (DL) operating at 1470 nm for spleen surgery in a pig model by analyzing the effectiveness of hemostasis and cutting, as well as the breadth of the thermal damage zone.
研究成果
Both the thulium-doped fiber laser (TDFL) and the diode laser (DL) are efficient in spleen surgery, providing good hemostasis. However, TDFL produces a narrower zone of thermal damage, suggesting its better efficiency for spleen surgery, especially when performing more precise procedures.
研究不足
The study was conducted on a pig model, which may not fully replicate human spleen surgery conditions. The sample size was limited to 12 animals, and the study focused on short-term outcomes (up to 14 days post-surgery).
1：Experimental Design and Method Selection:
The study compared two surgical lasers, a thulium-doped fiber laser (TDFL) at 1940 nm and a diode laser (DL) at 1470 nm, for spleen surgery in a pig model. The lasers were used to perform partial splenectomy and spleen incisions in 12 animals. Hemostasis was evaluated visually during surgeries, and post-mortem and histopathological evaluations were conducted on days 0, 7, and 14 following surgery.
2：Sample Selection and Data Sources:
The experiments were conducted on 12 female pigs of Large Polish White breed aged 10 weeks and weighing approximately 30 kg. The animals were acclimatized for 14 days before the experiment.
3：List of Experimental Equipment and Materials:
The lasers used were a thulium-doped fiber laser (TDFL) emitting at 1940 nm and a diode laser (DL) operating at 1470 nm. The power of the TDFL was 21 ± 1 W and the DL was 50 ± 1 W. The laser probes were moved along the spleen's surface at a constant average speed of 3.34 ± 0.38 mm/s.
4：34 ± 38 mm/s.
Experimental Procedures and Operational Workflow:
4. Experimental Procedures and Operational Workflow: The animals were sedated and underwent general anesthesia. A midline incision of the abdominal wall was made to access the spleen, which was then pulled out and placed on sterile gauze. A partial resection with DL or TDFL and an incision of the spleen with DL and then with TDFL were performed. The excised fragments of the spleen were harvested for histopathological evaluation immediately after cutting.
5：Data Analysis Methods:
The width of the thermal damage zones was measured from histopathological sections. Data were analyzed by Student’s t-test using the Statistica for Windows Version 10.0 software package.
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