摘要： The highly luminescent CdSe/CdS/ZnS core?multi-shell quantum dots (QDs) were prepared without a protective atmosphere through the precursor injection method (phosphine free) in paraffin liquid and oleic acid. Polymers (PEG, PVA, PVP, and PAA) were coated to CdSe/CdS/ZnS core?multi-shell quantum dots to increase stability. However, core?multi-shell structured QDs reveal enhanced emission in the range 355?410 nm by suppressing the defect sensitive cores and nonradioactive recombination in PL spectra. The cubic zinc blended quantum dots with crystallite size in the range 22?44 nm, as confirmed by XRD, were obtained. The resultant absorption spectra of all the samples showed that the samples were absorbent in the UV region over the 302?380 nm range. In the FT-IR spectrum 712, 731, and 400?700 cm?1 band values were assigned to CdSe, CdS, and ZnS band stretching, respectively. Images of CdSe, CdSe/CdS, and CdSe/CdS/ZnS quantum dots obtained from the SEM were spherical whereas QDs capped with different polymers (PEG, PVA, PVP, and PAA) showed nanofibers that were linear and homogeneous size ranged between 12 and 38 nm. These as prepared QDs were placed under visible light for 48 h. After absorbing UV light, the range of UV?vis intensity was enhanced until 389?464 nm and emission intensity enhanced until 492?509 nm, which was confirmed by UV and PL spectra. CdSe/CdS/ZnS QDs with organic ligands revealed antibacterial activity over a broad range against Klebsiella Pneumoniae and Pseudomonas aeruginosa.