研究目的
Investigating the properties of speckle and evaluating image processing methods for monitoring blood flow in vivo.
研究成果
The developed time-integrated dynamic speckle simulation method is effective for investigating the properties of speckle and evaluating image processing methods for monitoring blood flow in vivo. The method allows for the study of speckle size effects on LSCI and provides optimal parameters for obtaining accurate and less noisy images.
研究不足
The simulation method requires adjustment of correlation coefficients to mimic specific flow conditions, and the optimal speckle size for accurate imaging is constrained by the Nyquist criterion.
1：Experimental Design and Method Selection:
A time-integrated dynamic speckle simulation method based on coherent imaging was developed. The method involves generating a sequence of statistically independent W values with a specific correlation to simulate dynamic speckle patterns.
2：Sample Selection and Data Sources:
The simulation involves generating speckle images with pre-defined correlation distributions to mimic blood flow in vessels.
3：List of Experimental Equipment and Materials:
MATLAB was used for writing the simulation program.
4：Experimental Procedures and Operational Workflow:
The simulation involves generating a sequence of speckle images with correlation coefficients adjusted to mimic the temporal changes of speckle patterns due to Brownian motion and laminar flow.
5：Data Analysis Methods:
The correlation between speckle images was analyzed to validate the simulation method, and the effect of speckle size on laser speckle contrast imaging (LSCI) was investigated.
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