研究目的
To test the possibility of selective detection of furfural (2-FAL) in aqueous solutions, with a molecularly imprinted polymer (MIP) receptor exploiting two different transduction methods, for food safety applications.
研究成果
The electrochemical sensor detects 2-FAL in aqueous solution at concentrations from about 3 × 10?6 M to 1 × 10?2 M, while the SPR sensor's detection range is from 1 × 10?7 M to 1 × 10?4 M. The SPR sensor sensitivity is very low at concentration higher than about 1 × 10?5 M. The electrochemical sensor shows an LOD of about 6 × 10?6 M for 2-FAL in water, which is almost one order of magnitude higher than that obtained by the SPR sensor.
研究不足
The heterogeneity of MIP may diminish the performance in some analytical application, but it can be interesting in the case of sensing since it could make the coupling with different transduction methods possible. The detectable concentration level depends on the sensitivity of the detection technique employed.
1:Experimental Design and Method Selection:
The study examines a solid synthetical receptor obtained by non-covalent molecular imprinting of 2-furaldheide (2-FAL) connected with two different transduction methods: electrochemical and surface plasmon resonance (SPR).
2:Sample Selection and Data Sources:
The study focuses on the detection of 2-FAL in aqueous solutions, relevant for beverages.
3:List of Experimental Equipment and Materials:
Screen printed electrochemical cell (SPC) for electrochemical sensors and a D-shaped plastic optical fiber (POF) for SPR sensors.
4:Experimental Procedures and Operational Workflow:
The MIP layer is deposited over the transductor (chip) for both sensor types. The electrochemical sensor measures peak current (ip) obtained by square wave voltammetry (SWV), while the SPR sensor measures the variation of the resonance wavelength (Wav shift).
5:Data Analysis Methods:
The signal from the electrochemical sensor is directly proportional to the analyte concentration in the polymeric layer near the working electrode. The SPR sensor's signal is due to the variation of the refractive index of the MIP layer on the gold film.
独家科研数据包,助您复现前沿成果,加速创新突破
获取完整内容