研究目的
The primary goal of this study was to identify characteristic features of peripheral degenerative retinoschisis (RS), schisis detachment (SD) and retinal detachment (RD) on both fundus autofluorescence (FAF) and infrared (IR) imaging, using spectral domain optical coherence tomography (SD-OCT) imaging of the peripheral retina as the confirmatory imaging tool.
研究成果
In conclusion, the combination of FAF, IR imaging, and SD-OCT, along with clinical findings found on fundus examination with scleral depression are helpful in diagnosing, monitoring and managing RS, SD, and RD. OCT however remains the main modality imaging to differentiate these conditions. In the future, the use of ultra-widefield OCT and peripheral OCT images will allow better diagnostic accuracy of identifying and differentiating RS, SD and RD.
研究不足
Our study was limited due to the small sample size and that Optos AF was used late in the study, therefore, the Optos images were not used for data analysis. Also, only a small portion of the patients followed up regularly throughout this two-year study, which limited the use of three modes of imaging for monitoring progression of lesions. Finally, the use of peripheral OCT requires cooperation of the patient and a skillful photographer to maintain the same angle during each study, which affected its consistency as a gold standard for monitoring lesion progression.
