研究目的
Investigating the reduction of out-of-plane artifacts and providing a three-dimensional view of out-of-plane absorbers in photoacoustic imaging using a laser-integrated linear-transducer-array probe.
研究成果
The study demonstrates a three-dimensional (3D) reconstruction approach by using axial transducer array displacement, which provides a 3D view of out-of-plane absorbers and reduces OPAs in the in-plane image. The method shows promising clinical applicability, especially with the improvement of reconstruction by taking the sensitivity of the transducer array into account.
研究不足
The 3D reconstruction using axial displacement cannot show in-plane absorbers in an elevationally correct manner. All in-plane absorbers appear in a curve shape elevationally. The method is also limited by the number of displacement positions, which might lead to strong streak-type reconstruction artifacts.
1：Experimental Design and Method Selection:
The study uses axial transducer array displacement to identify and remove out-of-plane artifacts (OPAs) and to provide a three-dimensional (3D) view of the OPAs. The method involves back-projection and multiplication (BPM) for 3D reconstruction.
2：Sample Selection and Data Sources:
Phantom and in vivo experiments were conducted using an integrated PAI probe. A black nylon absorber and a volunteer’s finger with a black ink mark were used as samples.
3：List of Experimental Equipment and Materials:
A handheld PAI probe with integrated lasers, a commercial US scanner MyLabOne, motorized translation stages (MTS50A-Z8), and a black suture (USP 5/0, Vetsuture Nylon) were used.
4：Experimental Procedures and Operational Workflow:
The transducer array was displaced axially while the sample and light source were fixed. Data was acquired at multiple displacement positions, and 3D projections were formed by back-projecting the RF signal of all transducer elements volumetrically.
5：Data Analysis Methods:
The reconstructed pressure distribution images were analyzed using a Fourier transform based reconstruction algorithm. The signal-to-noise ratio (SNR) and artifact-to-noise ratio (ANR) were compared between direct back-projection (BP) and BPM.
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