研究目的
To provide a comprehensive review on the development of thin film-based nano-biosensors for uric acid determination, focusing on their application in arthritis diagnosis.
研究成果
The review concludes that thin film-based nano-biosensors are highly sensitive and suitable for early diagnosis of diseases related to abnormal uric acid levels. Enzyme immobilisation and the use of polymer nano-composites with metal oxide thin films enhance biosensor sensitivity and efficiency.
研究不足
The review highlights the challenges in biosensor development, such as interference effects from other analytes, the need for enzyme immobilisation to preserve activity, and the complexity of some fabrication methods.