研究目的
To assess long-term changes in the flow parameters of retrobulbar vessels in diabetic patients.
研究成果
The study demonstrates that an increase of resistance in the retrobulbar vessels, as part of DR, can lessen over time and may even be reversed, contradicting the commonly accepted theory that RI increases with disease progression.
研究不足
The main limitation is the small sample size due to the long-term follow-up of old-age patients with DM, many of whom died during the study. Partial data regarding some patients and exclusion of certain measurements (PSV, EDV, blood pressure, intraocular pressure) also limit the study.
1：Experimental Design and Method Selection:
The study is a historical prospective study comparing baseline data from 1994-1995 with follow-up data from 2004-
2：Color Doppler imaging (CDI) was used to assess flow velocities in the major retrobulbar vessels. Sample Selection and Data Sources:
20 138 eyes were initially evaluated, with 36 eyes from 19 patients reevaluated after 10 years. Participants were divided into four groups based on diabetic retinopathy (DR) status.
3：List of Experimental Equipment and Materials:
Acuson128XP10 with a
4：5 MHz linear transducer (1994-1995) and ATL HDI 5000 with a multifrequency 7–12 MHz linear array probe (2004-2008). Experimental Procedures and Operational Workflow:
CDI examinations were performed by the same sonographer at two time points. PSV and EDV of blood flow in the OA, CRA, and PCA were measured, and RI was calculated.
5：Data Analysis Methods:
Statistical analysis included paired t-tests, Pearson correlation tests, and one-way analysis of variance using SPSS.
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