研究目的
To achieve direct access to terminal enones via α-methylenation of aryl ketones under visible-light conditions using methanol as one carbon source substrate and solvent.
研究成果
The study presents a mild, efficient, and green protocol for the synthesis of terminal enones via α-methylenation of aryl ketones using methanol as a one-carbon source under visible-light conditions. The method features operational simplicity, wide substrate scope, and excellent yields.
研究不足
The reaction is limited to aryl ketones; aliphatic ketones like acetone did not yield the desired product due to high volatility.
1：Experimental Design and Method Selection:
The reaction involves Cu@g-C3N4-catalysed in situ oxidation of methanol into formaldehyde followed by dehydrative cross aldol type reaction under visible light conditions.
2：Sample Selection and Data Sources:
Various aryl ketones were used as substrates with methanol as the solvent and one carbon source.
3：List of Experimental Equipment and Materials:
Cu@g-C3N4 catalyst, K2CO3, PPh3, MeOH, and visible light source (7-volt LED light).
4：Experimental Procedures and Operational Workflow:
The reaction mixture was stirred under visible light at room temperature for 4-8 h. After completion, the catalyst was filtered, and the product was isolated and purified.
5：Data Analysis Methods:
The products were characterized by 1H and 13C NMR spectra.
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