摘要： Mammography is one of the broadly used imaging modality for breast cancer screening and detection. Locating mass from the whole breast is an important work in computer-aided detection. Traditionally, handcrafted features are employed to capture the difference between a mass region and a normal region. Recently convolution neural network (CNN) which automatically discovers features from the images shows promising results in many pattern recognition tasks. In this paper, three mass detection schemes based on CNN are evaluated. First, a suspicious region locating method based on heuristic knowledge is employed. Then three different CNN schemes are designed to classify the suspicious region as mass or normal. The proposed schemes are evaluated on a dataset of 352 mammograms. Compared with several handcrafted features, CNN-based methods shows better mass detection performance in terms of free receiver operating characteristic (FROC) curve.