1：Experimental Design and Method Selection:

The study involved generating a light droplet illumination by interfering Bessel beams of specific k-vectors to suppress side lobes. The setup included a spatial light modulator (SLM) for beam modulation and objective lenses for Fourier transform and fluorescence signal collection.

2：Sample Selection and Data Sources:

Fluorescent spheres embedded in a fixed gel were used as the sample to demonstrate the imaging contrast enhancement.

3：List of Experimental Equipment and Materials:

The setup included an SLM (Holoeye LC2012), objective lenses (Olympus Plan N 10X, Zeiss LD A-Plan 20x Ph1 M27), a tube lens (Thorlabs TTL200), a bandpass filter (Thorlabs FELH0550), and a CCD camera (Photometrics CoolSNAP HQ2).

4：2). Experimental Procedures and Operational Workflow:

4. Experimental Procedures and Operational Workflow: The wavefront of a laser beam was modulated by the SLM to generate the droplet illumination. The fluorescent signal from the sample was collected and detected to compare the imaging contrast between standard Bessel beam and droplet illuminations.

5：Data Analysis Methods:

The optical power and FWHM of the droplet side lobes were measured and compared with those of a Bessel beam. The imaging contrast was evaluated based on the fluorescence images obtained.