摘要： The necessary for energy always increases every year, so it is necessary energy alternative to overcome the phenomenon. From some alternative energy that is currently widely developed is solar energy. Unfortunately the use of solar energy with the help of solar panels produces power that varies according to the irradiation received and the temperature on the solar panel. Irradiation is the emission of energy coming from the sun. This parameter causes the output power characteristic curve to be non-linear. And the power generated by PV has not reached the maximum power point. To overcome this problem requires an arrangement to find the maximum power point and make it stable at that point. Therefore, this paper proposes "Comparison of First Order Differential Algorithms, Perturb and Observe(P&O) and Newton Raphson Methods for PV Application in DC Microgrid Isolated System" so that the maximum power point can be achieved quickly and accurately. In this paper we tried to compare 3 methods of First-order Differential, P & O (Perturb and Observe) and Newton Raphson by using ZETA Converter as its object in switching settings. By using the simulation can be obtained the results of tracking speed and maximum power level. The results of the simulation show that error power the First-order Differential is 4%, P & O is 0.26389% and Newton Raphson is 0.45178%. It is evident that Raphson's newton algorithm is superior to speed and accuracy.